Fracture Femur: A Case Report
Journal Title: Scholars Journal of Medical Case Reports - Year 2017, Vol 5, Issue 2
Abstract
Abstract: Gilbert’s syndrome is a form of hereditary non-hemolytic jaundice transmitted by autosomal dominant pattern. Due to low glucuronyl transferase activity in the liver, there is a risk for toxicity towards various anaesthetic agents. It is important for the anesthesiologists to understand the pathophysiology of the disease and the conditions leading to decreased glucuronyl transferase activity. Here we report anaesthetic management of a case of Gilbert’s syndrome with chronic malunited supracondylar fracture femur with fracture upper end of tibia, the principles of management in intraoperative and postoperative period. Minimal administration of intravenous drugs, maintaining the organ perfusion and postoperative pain relief using epidural anesthesia offers a safe conduct of anesthesia which can be considered as an alternative to general anesthesia and can avoid potential toxic effects of the agents metabolised by the liver. Keywords: Gilbert’s syndrome, general anesthesia, glucuronyl transferase.
Authors and Affiliations
Dr. Tanumoy Maulick, Dr. Sandhya Gujar, Dr. Snehal Kale, Dr. Karuna Sidam
Keywords
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