Fracture Risk Prediction in Outpatients from Krakow Region Using FRAX Tool Versus Fracture Risk in 11-year Follow-up
Journal Title: Ortopedia Traumatologia Rehabilitacja - Year 2013, Vol 15, Issue 6
Abstract
Introduction. FRAX is a an algorithm accepted by WHO for evaluating fragility fracture risk of women aged 40 years or more. The aim of this study was to use the FRAX tool to verify the risk of fractures in a population of women from the Cracow region in an 11-year follow-up.Materials and methods. The study was a retrospective cohort survey evaluating the incidence of fragility fractures over 11 years of follow-up. 5,092 women aged 50 years and more were randomly chosen from a group of 100,000 female patients of the Cracow Medical Centre who came to the Centre for densitometric examination between 1997 and 2001. Finally, 1024 patients were randomized into the study. After an average of 11 years a follow-up telephone survey was conducted among a randomly selected group of patients using a questionnaire corresponding to the one applied in the first survey. 10-year fracture risk was calculated for each patient using FRAX based on the BMI (Body Mass Index) and for 886 women using FRAX based on BMD (Bone Mineral Density) at the femoral neck. The Polish version of FRAX was validated by comparing the predicted risk with the actual incidence of fractures during the 11-year follow-up.Results. The 10-year probability of a major osteoporotic fracture calculated using FRAX based on BMI for the entire group was 5.3% (median, 1st/3rd quartile: 3.5-8.5%) and the probability of a proximal femur (hip) fracture was 1.3% (median, 1st-3rd quartile: 0.7% -2.4%). In 886 women whose BMD T-score at the femoral neck was available, the mean probability of a major osteoporotic fracture was 4.9% (3.3-7.9%) and of a hip fracture 0.9% (0.3-2.3%). The actual absolute fracture risk calculated on the basis of the number of patients who had experienced a fracture during the follow-up was surprisingly much higher than the predicted figure. The risk of a major fracture in the study group was 17.7% and of a proximal femur fracture, 3%.Conclusion. In our opinion, FRAX is a very good screening tool, but not a precise diagnostic tool.
Authors and Affiliations
Edward Czerwiński, Przemysław Borowy, Anna Kumorek, Jarosław Amarowicz, Maciej Górkiewicz, Agata Milert
Keywords
Related Articles
- EP ID EP57349
- DOI -
- Views 105
- Downloads 0
Importance of Computed Tomography (CT) in Talar Neck Fractures. Case Studies
Computed tomography is a modern technique producing high quality image of scanned organs. It plays a significant role in diagnostic work-up on orthopedics wards. This paper presents an analysis of management of two cases...
Taktyka postępowania operacyjnego i wyniki leczenia pacjentów ze zmianami zwyrodnieniowymi w przebiegu wrodzonego wysokiego zwichnięcia stawów biodrowych
[b]Materiał i metoda.[/b] Autorzy omawiają wczesne (obserwacja 4 letnia) wyniki leczenia operacyjnego 18 stawów biodrowych u 14 kobiet średnia wieku 38 lat., z wysokim przemieszczeniem bliższego końca kości udowej po prz...
Outcome treatment of pseudoarthrosis of long bones with decortication method depends on morfology of pseudoartrosis
Introduction. Purpose of work was estimation of the results of treatment of pseudoarthrosis of the long bone with the method of decortication, with use of autogenic bone depends of kind of pseudoartrosis..Material and m...
Evaluation of blood loss and significance of postoperative autotransfusion in knee joint alloplasty
Introduction. The aim of this paper is to evalute perioperative blood loss associated with total cemented knee joint alloplasty, with special regard to specific factors that may influence this loss. Additionally, the sig...
Minimally invasive surgery in total hip arthroplasty
The success of orthopedic surgery depends on quick recovery of limb function. Every injury to a muscle or its attachment is associated with decreased muscle strength and disturbed proprioception, impeding recovery. Minim...