Free Radical Scavenging Activity of Jatropha curcas Leaves, Phytochemical and Antibacterial Analysis of Its Butanol Crude Extract
Journal Title: Asian Journal of Chemical Sciences - Year 2017, Vol 3, Issue 4
Abstract
The use of different plant parts for the prevention and cure of ailments, infections and diseases as an alternative to the use of orthodox medicine is gaining more attention. Moreso, resistance to orthodox drugs has been confirmed in various literature. The free radical scavenging activities of Jatropha curcas (Euphorbiaceae) leaves, phytochemicals present in its butanol crude extract as well as the antibacterial activities of its butanol crude extract were accessed. The leaves of Jatropha curcas were washed, air-dried and pulverized for active extraction of the composition of the plant in butanol. Fresh leaves of the plant were tested for its DPPH (2,2-Diphenyl-1-picrylhydrazyl) scavenging activity (indicator of antioxidant), while the butanol crude leaf extract was accessed for the presence or absence of phytochemicals and was also tested against some gram positive and gram negative bacteria all according to standard procedures. All analysis was carried out at the Chemistry Laboratory of the Federal College of Animal Health and Production Technology, Moor Plantation, Ibadan for four weeks. The result of the free radical scavenging activity of the leaves (74.73 mg/kg) was higher than that of ascorbic acid (31.01 mg/kg) (a standard antioxidant). The qualitative analysis showed the presence of alkaloids, tannins, saponin, flavonoids, steroid, phenols phlobatanins and cardiac glycoside. The quantitative analysis on the other hand showed the presence of alkaloids in an appreciable amount (0.567%), followed by saponin (0.316%) while others had relatively low values (below 0.19%). The average values of the antibacterial (inhibitory) activity as compared with standard antibiotics used had no significant difference except for Pseudomonas sp. which was very low to the antibiotics used. It could be concluded that Jatropha curcas is of great medicinal potential.
Authors and Affiliations
Qasim Olaitan Afolabi, Adijat Yetunde Shorinmade, Ofunami Joy Obero
Keywords
Related Articles
- EP ID EP338855
- DOI 10.9734/AJOCS/2017/38036
- Views 118
- Downloads 0
In Vitro Antioxidant Properties of Novel Schiff Base Complexes
Aim: In order to identify and evaluate the metal-derived synthetic antioxidants having high free radicals scavenging capacity related to various disorders has received much interest in last decades. Recently, synthetic a...
Free Radical Scavenging Activity of Jatropha curcas Leaves, Phytochemical and Antibacterial Analysis of Its Butanol Crude Extract
The use of different plant parts for the prevention and cure of ailments, infections and diseases as an alternative to the use of orthodox medicine is gaining more attention. Moreso, resistance to orthodox drugs has been...
Isolation and Characterisation of Stigmasterol and β–Sitosterol from Anthocleista djalonensis A. Chev.
Aim: Anthocleista djalonensis A. Chev. is a plant with several chemical constituents which accounts for its ethno-pharmacological uses. The present study is aimed at identifying and characterizing the active principles f...
New Synthetic Pathways for Thiocarbohydrazide and Salicylaldehyde Azine Compounds
Thiocarbohydrazide synthesis is an important intermediate step for many hydrazine organic synthetic reactions. Synthesis of thiocarbohydrazide can be done by reaction of carbon disulfide with hydrazine (hydrazinolysis) i...
Solubility of Benzoic Acid in Six Alcohols within (288.15 to 336.15 K) and Thermodynamic Properties in the Dissolution Process
The solubility of benzoic acid was determined in six alcohols (isobutanol, n-pentanol, isoamylol, 2-pentanol, tert-amyl alcohol and n-hexanol) from (288.15 to 336.15 K) by the dynamic method. The value of solubility rise...