Frequency of Common Pathogens Isolated from Open Fractures of the Extremities and their Antimicrobial Sensitivity Pattern.
Journal Title: Journal of Pakistan Orthopaedic Association - Year 2020, Vol 32, Issue 04
Abstract
Objective: To determine the frequency of micro organisms in open fractures of the extremities and their sensitivity pattern to the commonly used antibiotics. Methods: This descriptive study was conducted in the Department of Orthopaedic Surgery Nishtar Medical University Hospital Multan. The duration of our study extended from 29th June 2019 to 5th July 2020. Patients of either gender and age 18 to 60 years with open fractures meeting the inclusion criteria were enrolled in our study. Wound swabs were taken with Levine technique before surgical debridement and sent to laboratory for Gram staining and culture and sensitivity of the microbial agents. Post stratification comparison of important variables were done and P value was calculated with the help of Chi-square test. ( P<0.05 was considered statistically significant) Results: The total number of patients in our study were 195.Male patients were 161(82.6%) and female 34(17.4%). The mean age was 38.86±8.05 years. The most common fractured bone was tibia (20.5%, n=40) followed by humerus (19%, n=37%) and metacarpals/phalanges (16.9%, n=33). Gustilo Anderson type IIIA was the predominant type of fracture present in 71(36.4%) patients followed by type II (27.2%, n=53).Majority (62.6%, n=122) of the patients were presented to the hospital in time period extending from 6-12 hours of sustaining the injury. The culture report was positive in 187(95.8%) patients while no growth was noted in 8(4.1%) patients. Staphylococcus Aureus was reported in 112(57.4%) patients, Streptococcus in 34(17.4%) and E. Coli in 22(11.3%). Gram positive cultures were most sensitive to first generation Cephalosporin (60.5%, n=118) while Gram negative cultures to Quinolones (69.4%, n=25). Conclusion: Majority of open fractures of the extremities had positive culture of bacteria. Gram positive organisms were the most common isolated pathogens. First generation Cephalosporin was the most sensitive group of drugs against gram positive bacteria.
Authors and Affiliations
Tariq Mahmood1, Mukhtar Ahmad Tariq2, Muhammad Badar uddin Zafir3, Muhammad Khalid Chishti4, Muhammad Shafee5, Azmat Rasool6
Keywords
Related Articles
- EP ID EP741531
- DOI -
- Views 49
- Downloads 0
Management of Earthquake Victims at Disaster Places
The government would start the functions of an agency in collaboration with medical societies, and make a plan to educate and prepare well trained nation to be able to manage disaster victims. Place and Duration of St...
Risk Factors of Low Backache in Patients Presenting to A Tertiary Care Hospital of Dera Ismail Khan, Pakistan
Background: Low back pain (LBP) is a leading cause of disability worldwide. The objective of this study was assessment of risk factors of low backache in patients presenting to a tertiary care hospital. Methods: This...
Functional Outcome of Closed Humeral Shaft Fractures Treated with Functional Brace.
Objective: To determine the functional outcome of closed humeral shaft fractures treated with functional brace. Methods: This descriptive study was conducted in Orthopedic Department District Headquarter hospital Teac...
Early Functional Outcome: Comparison Between Bipolar and Unipolar Hemiarthroplasty
Objective: To compare Bipolar and unipolar hemiarthoplasty (HA) treatment for neck of femur fracture in elderly population. Methods: This is a descriptive randomized study, conducted from January 2014 to May 2015. All...
Outcome Analysis of Hip Arthroscopy
Hip arthroscopy has evolved significantly over last two decades. Many procedures are being done arthroscopically as our understanding increases. However, in many countries, including Pakistan, Hip arthroscopy is in its i...