Frequency of NAFLD in Bangladeshi Subjects with Metabolic Syndrome and Its Association with Components of Metabolic Syndrome
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH - Year 2016, Vol 8, Issue 5
Abstract
Objective: Nonalcoholic fatty liver disease (NAFLD) is considered as the principal cause of chronic elevated liver enzymes. The components of metabolic syndrome are found to be significantly associated with NAFLD. The study was carried out to determine association between nonalcoholic fatty liver diseases and components of metabolic syndrome. Methods: This cross sectional observational study was conducted with ethical permission, between April 2015- September 2015, among randomly collected 203 Bangladeshi subjects with Metabolic Syndrome, aged >18 years, who visited Out Patient Department (OPD) of MARKS Medical College & Hospital, Dhaka. In the study, Adult treatment Panel (ATP) III criteria was used to diagnose metabolic syndrome and 4D abdominal ultrasonography were performed to detect fatty infiltration in the liver. Data were collected in pre-formed record form, analyzed with SSPS for Windows version 16. Results: Presences of NAFLD among subjects with metabolic syndrome were evaluated by abdominal 4D ultrasonography. Frequency of NAFLD was 26.60%. Women had more NAFLD (55.55%) than men. Men were more overweight than female and female were more obese than male [p0.023]. Waist-hip ratio (WHR) were more in subjects with NAFLD [0.96±0.02 vs 0.94±0.04, p0.001) and High Density Lipoprotein (HDL) cholesterol were significantly less in subjects with NAFLD (36.97±3.52 vs 40.93±6.89, p0.002) than subjects with non-NAFLD. Conclusion: The components of metabolic syndrome are found to be closely linked with NAFLD. In this study, high WHR and low HDL cholesterol were significantly associated with NAFLD.
Authors and Affiliations
Akter, N. ,, Ferdous , H. S. , Qureshi, N. K.
Keywords
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