Fruits and Vegetables as Dietary Sources of Antimutagens
Journal Title: Journal of Food Chemistry and Nanotechnology - Year 2016, Vol 2, Issue 3
Abstract
Mutation is the process leading to heritable changes in the genetic material of an organism and caused mainly by the external factors, including chemical and physical agents, or can also occur spontaneously due to errors in DNA replication, repair, and recombination. Agents contributing to the mutagenic burden in the environment could be from industrial sources, wide spectrum applications of biocides in the agriculture, and other contaminants. As many of these mutagenic chemicals can induce severe disorders in humans including cancer and a large spectrum of inherited diseases, it is important to detect such mutagenic agents precisely and rapidly, and also look for an approach to combat them. Natural occurring dietary antimutagens primarily from health protective foods such as fruits and vegetables could provide a mechanism to counteract the deleterious effect of these mutagens. The World Health Organization (WHO) indicates that one-third of all cancer deaths are preventable and that diet is closely linked to cancer prevention. These health protective phytochemicals particularly antimutagenic ones could provide an effective solution to these concerns. The current review deals with understanding of the mutagenic events, methods of its analysis and a brief compilation of the existing scientific findings related to the dietary sources having potential to counteract the effects of the mutagenic exposures from different sources. The review would provide an opportunity to look into the science, think about the possible future perspectives and mechanism to translate the outcome of the scientific research for benefits of the mankind.
Authors and Affiliations
Satyendra Gautam, Sudhanshu Saxena, Sanjeev Kumar
Keywords
Related Articles
- EP ID EP223303
- DOI 10.17756/jfcn.2016-018
- Views 108
- Downloads 0
Polydiacetylene Vesicles for Detecting Surfactants: Understanding the Driven Forces of Polydiacetylene- Surfactant Interaction
Surfactants are widely used by food industry thus its discharge is an environmental concern; and development of Polydiacetylene (PDA)-based sensors may detect these molecules. However, to improve the sensor efficiency is...
Proceedings of the First Probiotics Summit (PBS-2015)
Women worldwide continue to be infected with HIV at an alarming rate. The majority of Human Immunodeficiency Virus (HIV) infections occur by the mucosal route during unprotected vaginal sexual intercourse.
Proceedings of the III International Conference on Food Chemistry & Technology (FCT-2017)
A process was begun in the mid-1980’s to develop methods for evaluating the safety of foods produced in genetically modified (GM), or genetically engineered crops used to produce foods.
Report on the First Probiotics Summit 2015 (PBS-2015)
Probiotics Summit 2015 (PBS-2015) concluded successfully on July 08, 2015. The three day summit was organized by United Scientific Group (USG) during July 06-08, 2015 at DoubleTree By Hilton, San Francisco, USA. PBS- 201...
A Review on Microextraction Techniques for Selected Triazole Fungicides Determination in Water and Food Samples
Triazole fungicides are systemic fungicides applied to protect crops from fungus infections. Its use must be controlled due to the potential harmful effects in environment and human health. Before determination with a ch...