Fungal Keratitis – Epidemiology and Treatment Outcome - In North Costal Andhra Pradesh
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 5
Abstract
Purpose: To review the distribution, current trends, and response patterns for treatment of fungal keratitis isolates in costal districts over the last 2 years Methods Design: Retrospective, observational, case series. Participants: Microbiology records of suspected fungal keratitis cases that underwent a diagnostic corneal scraping and cultures from March 1,2010, through April 31, 2012,at sankar foundation eye hospital, teritiary eye care and referral center, were reviewed. Culture results and medical and surgical management response were reviewed and analyzed. Results: A total of 450corneal scrapings were taken during the 2years of the study. Pathogen was recovered in 380 samples (84.4%), with fungal keratitis accounting for 350 of the positive cultures (81.5%). Asperigillus 48.15%, Fusarium 43.15%, Yeast 0.2%, Paecillomysis0.52%, and Acremonium 0.52%, not able to grow in 7.63%. Out of 380 cases 315 cases responded for topical antifungals, 75 cases with deep infiltrates and endoexudates resistant to topical medication alone, 33cases posted for TPK , 42cases treated with intracameral Ampho-B 10-15 u and intrastromal 7.5microns at least 2-3 times along with oral anti fungals. Conclusions: 1. About 90% h/o of injury with vegetable matter,2.Pts who presented early are responded very well with Natamycin 5%e/d and Fluconazole e/d along with repeated superficial debridement . If not responding addition of Amphotericin B 0.2%e/d hrly is with good results, 3.Deep infiltrates and endoexudate cases those who were given intracameral and intra stromal along with oral azoles doing well than TPK patients after optical PKP. 6. Topical Voriconazole 20% e/d (aurolab) did not give any added advantage except in few cases. 7.Pts on steroids were refractory to maximum medical treatment ultimately going for surgical intervention.
Authors and Affiliations
Dr Veena. P
Keywords
Related Articles
- EP ID EP285276
- DOI -
- Views 76
- Downloads 0
An Etiological Study of Upper Gastro-intestinal Bleeding with Special Reference to Helicobacter Pylori Infection in Peptic Ulcer Disease
OBJECTVE: Upper gastro intestinal bleeding is a common life threatening emergency resulting in a large number of hospital admission. Peptic ulcers are the most common cause of UGIB. Helicobacter pylori plays a pivotal ro...
Impact of Water Based Exercises on Balance in Elderly Women
Aging has been shown to affect all of the systems causing poor balance in elderly subjects. Elderly subjects present serious problems due to poor balance such as falls and fractures which increase economical costs in hea...
A Case of Common Extensor Tendon Tear of Elbow Treated with Platelet Rich Plasma Infiltration
Common Extensor tendinopathy is one of the most common overuse injury of elbow. With the repetitive overload and microtrauma of elbow it may eventually leads to tear of the common extensor tendon that is rare. In this ca...
Assessment of Some Health-Related Practices and Knowledge among a Group of Egyptian Patients with Peptic Ulcer Disease
Background: Peptic ulcer disease had a tremendous effect on morbidity and mortality until the last decades of the 20th century, when epidemiological trends started to point to an impressive fall in its incidence due to t...
Metatarsophalangeal (MTP) Joint Pathology Management by Arthroscopy
Arthroscopic surgery is one of the basic types of procedures in orthopedic surgery. The present study describes 10 arthroscopies of the first metatarsophalangeal (MTP) joint in 10 patients over a 5 year period. Their mea...