Gamma-Delta T Cell Acute Lymphoblastic Leukemia: A Single-Center Experience

Journal Title: Global Journal of Cancer Therapy - Year 2016, Vol 2, Issue 1

Abstract

Gamma-delta (γδ) T cell neoplasms are a rare disease entity characterized by an aggressive clinical course [1,2]. The management of these neoplasms associated with high incidence of induction failures and poor clinical outcomes [3]. Here we present two cases of gamma-delta T cell acute lymphoblastic leukemia (γδ T-ALL) successfully treated with chemotherapy and allogeneic stem cell transplant at our institution. We also review the literature and summarize what is known about this disease. In our experience, induction chemotherapy followed by allogeneic stem cell transplantation has been an effective strategy in producing durable remissions.

Authors and Affiliations

Donnellan W, Mineishi S, Wicker J, Paluri R

Keywords

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  • EP ID EP352863
  • DOI 10.17352/2581-5407.000010
  • Views 119
  • Downloads 0

How To Cite

Donnellan W, Mineishi S, Wicker J, Paluri R (2016). Gamma-Delta T Cell Acute Lymphoblastic Leukemia: A Single-Center Experience. Global Journal of Cancer Therapy, 2(1), 26-29. https://europub.co.uk/articles/-A-352863