Gastrointestinal Stromal Tumors: Experience from a Single Surgical Unit
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 5, Issue 10
Abstract
Background: Gastrointestinal stromal tumors (GISTs) are rare tumors, but comprise the most common mesenchymal neoplasms of the gastrointestinal (GI) tract. We report a clinical series of abdominal GIST and discuss the diagnosis and management in Indian patients. Case Series: The data on demographic profile, clinical presentation and management of 12 cases of GIST from a single surgical unit in the last seven years were studied retrospectively. Preoperatively, ultrasonographic and computerized tomographic scans of the abdomen were the main investigations used for evaluation; the others being upper gastrointestinal endoscopy and X-ray of the chest. Histopathological examination and immunohistochemical evaluation were used to confirm the diagnosis. Results: The mean age at presentation was 47.9 years (range 35 – 70 years). Mean duration of symptoms was of 5 months (range 10 days–2 years). While all 12 patients presented with abdominal pain, 10 complained of abdominal lump. Two patients complained of vomiting and 1 of upper GI bleed. All patients were operated. In 7 cases, the GIST was arising from the ileum, 3 from the stomach and 2 from the mesentery. Nine cases had low grade benign tumors and 3 had malignancy. Conclusion: Abdominal pain and lump are the most common clinical symptoms of abdominal GIST. Vomiting, upper GI bleeding and weight loss are among the other important symptoms. Most of the tumors are benign and surgical resection remains the mainstay of treatment.
Authors and Affiliations
Satendra Kumar, Satyanam Kumar Bhartiya, Somprakas Basu, Mohan Kumar, Vijay Kumar Shukla
Keywords
Related Articles
- EP ID EP347186
- DOI 10.9734/BJMMR/2015/13856
- Views 58
- Downloads 0
Knowledge of Lassa Fever among Students of a College of Education: Call for Inclusion in Curriculum
Aims: To determine the level of knowledge of Lassa fever among students of a Federal College of Education. Study Design: A descriptive, cross-sectional study. Place and Duration of Study: Adeyemi College of Education, O...
Prevalence of ACS and Causal Relation of Hypomagnesaemia
Magnesium is an important intracellular cation [1], actually the second most abundant cation after Potassium, which has gained an essential role in normal human homeostasis. Low serum magnesium has been detected commonly...
Semen Characteristics of Male Infertile Couples in the Kumasi Metropolis: A Study of Primary and Secondary Infertile Couples
Aims: To assess the semen characteristics of primary and secondary male infertile couples in the Kumasi metropolis. Study Design: A cross-sectional study. Place and Duration of Study: Department of Obstetrics and Gynaec...
Clinical Evaluation of Class I Restorations Made with Composite with Low Degree of Polymerization Shrinkage
Aims: The objective of this study was to clinically evaluate the performance of a conventional resin system and one with low polymerization shrinkage. Study Design: A prospective, randomized, blind, split-mouth study....
Ultrastructure of Teleost Retina II: Interstitial Amacrines, Dislocated Amacrines, Ganglion Cells, Müller Fiber, Oligodendroglia, Adrenergic Terminals, Inner Plexiform Layer, Glycogen Cytochemistry
Aims: To analyze the ultrastructure of internal interstitial amacrine cell, dislocated amacrine cell, ganglion cells, oligodendroglia, Müller cells, inner plexiform layer, adrenergic terminals, as well as the connections...