Gastrointestinal symptoms associated with gastroesophageal reflux disease, and their relapses after treatment with proton pump inhibitors: A systematic review
Journal Title: Electronic Physician - Year 2017, Vol 9, Issue 6
Abstract
Gastroesophageal reflux disease (GERD) is a common functional gastrointestinal disorder with significant effects on the quality of life. The burden of GERD is soaring in Asia. Preventing symptom relapse is a therapeutic goal in GERD patients. Since proton pump inhibitors (PPI) are the first-line treatment of GERD, drug failure has become a major problem in the treatment procedure. We reviewed the literature in order to find articles related to comorbidities and symptoms affecting GERD from 1980 to 2015 via PubMed and Google Scholar using keywords such as 'Gastroesophageal reflux disease', 'Gastrointestinal symptoms' and Boolean operators (such as AND, OR, NOT). Due to the cost of PPI therapy and the high rate of GERD relapse after PPI therapy, demand for continuing this type of treatment is decreasing. Thus, we need to discover new approaches to treat the disease and also investigate the relationship between the treatment of GERD and its comorbidities and symptoms such as functional constipation
Authors and Affiliations
Mousalreza Hosseini, Roshanak Salari, Somayeh Shariatmaghani, Batul Birjandi, Masoumeh Salari
Keywords
Related Articles
- EP ID EP322044
- DOI 10.19082/4597
- Views 96
- Downloads 0
Competence of nurses in the intensive cardiac care unit
INTRODUCTION: Competence of nurses is a complex combination of knowledge, function, skills, attitudes, and values. Delivering care for patients in the Intensive Cardiac Care Unit (ICCU) requires nurses' competences. This...
Use of Artificial Neural Networks (ANNs) for the Analysis and Modeling of Factors That Affect Occupational Injuries in Large Construction Industries.
Occupational injuries as a workforce's health problem are very important in large-scale workplaces. Analysis and modeling the health-threatening factors are good ways to promote the workforce's health and a fundamental s...
Association between age associated cognitive decline and health related quality of life among Iranian older individuals
BACKGROUND: Age associated cognitive decline or normal cognitive aging is related with lower levels of functioning in real life, and may interfere with maintaining independence and health related quality of life (HRQL)....
Effect of six-week aerobic exercise on Chemerin and Resistin concentration in hypertensive postmenopausal women
Background: Physical activity reduces symptoms of cardiovascular diseases. The aim of this study was to examine the effect of six-week aerobic exercise upon Chemerin and Resistin concentration in women with menopause who...
Effects of Fenton Reaction on Human Serum Albumin: An In Vitro Study
INTRODUCTION: Human serum albumin (HSA) is a critical protein in human blood plasma, which can be highly damaged by oxidative stress. The aim of this study was to analyze modifications of this protein after oxidation usi...