GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SUDANESE CASSIA FISTULA LINN (CAESALPINACEAE) FIXED OIL
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2017, Vol 3, Issue 9
Abstract
Cassia fistula fixed seed oil was studied by GC-MS. The oil was also assessed for antimicrobial activity. Twenty five components were detected by GC-MS analysis. Main constituents are: 9, 12-Octadecadienoic acid methyl ester (24.46%); 9-Octadecenoic acid methyl ester (17.26%); Stigmast-7-en-3-ol (15.75%); Hexadecanoic acid methyl ester(13.55%) and Methyl stearate (7.75%). The antibacterial activity of the oil was evaluated via the diffusion assay against five standard human pathogens (Gram positive: Staphylococcus aureus and Bacillus subtilis; Gram negative: Escherichia coli and Pseudomonasa aeruginosa and the fungus Candida albicans). The oil was active against all test organisms in the range: 100 - 50mg/ml. On the basis of its promising antimicrobial activity, it seems that this oil is a lead for further opimization.
Authors and Affiliations
Dr. Abdel Karim M.
Keywords
Related Articles
- EP ID EP649560
- DOI -
- Views 170
- Downloads 0
DETERIMNATION OF AFLATOXINS IN GROUNDNUT (ARACHIS HYPOGEA) SOLD IN NNEWI MARKET, NNEWI NORTH L.G.A OF ANAMBRA STATE
Aflatoxins are potent toxic, carcinogenic, mutagenic immunosuppressive agent produced as secondary metabolites by some fungi causing aflatoxicosis in humans and animals.A total of 20kg of raw and boiled bold type of grou...
ISOLATION AND IDENTIFICATION OF HELICOBACTER PYLORI FROM CULTIVATED AND COMMERCIALLY SOLD VEGETABLES AND SALAD FROM SOME SELECTED TOWNS (NNEWI, AND ODEKPE) IN ANAMBRA STATE
Helicobacter pylori plays an important role in peptic ulcer disease and gastric carcinoma.This study was conducted to isolate and identify Helicobacter pylori from 64 cultivated and 60 commercially sold vegetables and sa...
CHEMISTRY AND CONSUMER PRODUCTS
It is almost impossible to comprehend all the products of chemistry that enrich our lives. It would be befitting to say that the ways in which the modern life differs most from that of earlier times resulted from the var...
DIVERSITY OF BIRDS IN THE MOIST LOWLAND FOREST OF BUNGUIAO AND DULIAN (UPPER BUNGUIAO), ZAMBOANGA CITY, PHILIPPINES
In the Philippines, nine (9) families of birds are extremely threatened and the Philippine Eagle is one of the critically endangered birds having 400 pairs left in the wild. Anthropogenic activities, like deforestation a...
A REVIEW ON “A CLINICAL APPROACH TO GINGER”
Ginger is a medicinal plant which has been widely used in Chinese, Ayurvedic and Unani herbal medicines all over the world and has a long history of use in traditional systems of medicine. Ginger, the rhizome of Zingier...