GC-MS ANALYSIS OF METHANOLIC EXTRACT OF LEAVES OF RHODODENDRON CAMPANULATUM

Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 12

Abstract

Objective: Rhododendron campanulatum is a native of high altitude and is known for its medicinal properties. The present study is aimed to identify the phytochemical constituents in the leaf extract of R. campanulatum using Gas Chromatography and Mass Spectroscopy (GC-MS).Methods: The methanolic leaf extract was prepared using Accelerated Solvent Extraction system at room temperature and high pressure. Phytochemical screening of methanolic extract of R. campanulatum was performed using GCMS-QP2010 Plus (Shimadzu, Kyoto, Japan) and the spectrum was interpreted on the basis of the databases of National Institute Standard and Technology (NIST11LIB) and WILEY8LIB. Results: The GC-MS analysis revealed the presence of 49 phytochemical compounds in the methanolic leaf extract. Baccharis oxide (9.99%), betuligenol (8%), alpha and beta-amyrin (7.38 and 2.64%), geranyl acetate (5.91%), (R)-(-)-14-methyl-8-hexadecyn-1-ol (5.19%) and phthalic acid (5.16%) were identified as major constituents.Conclusion: The methanolic leaf extract of R. campanulatum contains various phyto-compounds of pharmaceutical and industrial importance. 

Authors and Affiliations

Sakshi Painuli, Nishant Rai, Navin Kumar

Keywords

Related Articles

COMPARATIVE STUDY OF REVERSE WET GRANULATION WITH CONVENTIONAL WET GRANULATION IN SOLUBILITY ENHANCEMENT OF SIMVASTATIN

Objectives: Simvastatin is a cholesterol- lowering agent widely used in hypercholesterolemia. It belongs to BCS class II drugs having low solubility and high permeability. Simvastatin is practically insoluble in water an...

SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NOVEL SCHIFF BASES OF 2-QUINOLONES

A series of novel substituted 3-acetyl-1-(benzylideneamino) quinolin-2(1H)-one (1-12) have been synthesized by condensing different substituted 3-acetyl-1-amino-quinolin-2-one and aromatic aldehydes in alcohol medium. 3-...

ISOLATION AND QUANTIFICATION OF TANNINS FROM THE ROOT BARK OF CLERODENDRUM INFORTUNATUM LINN. AND ASSESSMENT OF THEIR ANTIOXIDANT POTENTIAL AND ANTIPROLIFERATIVE EFFECT ON HCT-15 CELLS

Objectives: Clerodendrum infortunatum is a traditional Indian medicinal plant which has been used for the treatment of many diseases. The root bark juice is effective against indigestion and abdominal pain. Based on the...

CHARACTERIZATION OF HYDRODISTILLATED POMELO PEEL OIL AND THE ENHANCEMENT OF BIOLOGICAL ACTIVITIES USING MICROEMULSION FORMULATIONS

Objective: The present study aims to investigate the compositions and biological activities of essential oil extracted from pomelo peel and develop into microemulsions.Methods: Four subspecies of pomelo including Kao-Nam...

PRESCRIBING PATTERN OF ANTIHYPERTENSIVE DRUGS BASED ON COMPELLING INDICATIONS WITH HYPERTENSION

Objective: The aim of the study is to assess the various prescribing patterns in hypertension with different compelling indications.Methods: It is a prospective observational study and carried out for a period of 1 y fro...

Download PDF file
  • EP ID EP578076
  • DOI -
  • Views 55
  • Downloads 0

How To Cite

Sakshi Painuli, Nishant Rai, Navin Kumar (2015). GC-MS ANALYSIS OF METHANOLIC EXTRACT OF LEAVES OF RHODODENDRON CAMPANULATUM. International Journal of Pharmacy and Pharmaceutical Sciences, 7(12), 299-303. https://europub.co.uk/articles/-A-578076