Gender Based Profiling of Opportunistic Infections in AIDS Patients in Tertiary Care ART Centre of A Cosmopolitan City of Central India
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 3
Abstract
Introduction: In HIV/AIDS, Women appeared to have more rapid progression of illness than men and to present with a different constellation of opportunistic infections than men. Objective of the study was to compare the gender difference in age distribution, marital status, presenting symptoms, Lab parameters and the AIDS defining infections and the opportunistic infections in men and women with AIDS. Material and Method: The study was carried out among 156 male, 82 female, and 1 transgender who fulfilled the NACO guidelines for diagnosis of AIDS. Results: The most frequent AIDS Defining Infections were tuberculosis (42.25%), and candidiasis (22.6%). In contrast to the western literature where Pneumocystis jiroveci pneumonia was commonest AIDS defining infections, we found that TB was commonest in our study. This is similar to other studies in India and other developing countries. Other conditions seen in this study were Herpes simplex (6.28%), nonspecific dermatitis (2.51%), recurrent bacterial pneumonia (1.67%) Pelvic inflammatory disease (1.25%), Cryptococcal meningitis (0.8%), CMV retinitis (0.4%) and non specific lymphadenopathy (0.4%). Pulmonary Tuberculosis (P = 0.001), Tubercular meningitis (P = 0.003) were significantly higher in males compared to females. Herpes simplex (P value 0.007) and non specific dermatitis (P value 0.01) showed statistically significantly higher in females compared to males in occurrence rate. Pelvic inflammatory disease is specific for females (p=0.01). Conclusion: Pulmonary Tuberculosis and Tubercular meningitis were significantly higher in males compared to females. Herpes simplex and non specific dermatitis showed statistically significantly higher in females compared to males in occurrence rate.
Authors and Affiliations
Vibhuti Thakur, Ashok Thakur, Shiv Shankar Sharma, Satish Saroshe
Keywords
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