GENDER DIFFERENCES IN OUTCOME FOLLOWING PRIMARY PERCUTANEOUS CORONARY INTERVENTION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 5
Abstract
BACKGROUND Women with ST elevation myocardial infarction had poor outcomes in prior fibrinolytic trials. We examined the impact of female gender on in-hospital as well as intermediate outcomes of primary PCI patients in a tertiary care centre. MATERIALS AND METHODS From January 2011 to December 2012, 576 consecutive patients undergoing primary PCI at a tertiary referral centre were included in a descriptive study. Clinical information was prospectively collected onto a database at the time of the procedure. Inhospital, 30-day and 6-month follow-up data were collected by review of records during review in OPD and through telephonic contact. Data was analysed with PSPP open source. RESULTS Female patients (16%) were (3 years) older than males. Females had higher incidences of diabetes (51% vs. 40%), systemic hypertension (56% vs. 38%) and dyslipidaemia (88% vs. 83%). Both anterior wall MI and inferior wall MI were equally represented in the study population, but more females were in cardiogenic shock (5.43% vs. 2.27%). Adjunctive medical treatment including GP IIb/IIIa blocker use was higher in men. The in-hospital incidence of MACE (10 (10.87%) vs. 29 (5.99%), p= 0.087) and death (9 (9.78%) vs. 25 (5.17%) p= 0.062) did not differ significantly between women and men. But there was a trend toward increased in-hospital mortality and MACE in women. The cumulative MACE events (11.96% vs. 6.2%) and mortality (10.87% vs. 5.37%) at six months was significantly more in women. CONCLUSION In this study, female gender did not emerge as an independent predictor for in-hospital MACE and mortality, but had higher MACE at six months follow-up.
Authors and Affiliations
Sunitha Viswanathan, Satheesan Praveen, Anup Kumar Sadanadan
Keywords
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- EP ID EP285921
- DOI 10.14260/jemds/2018/132
- Views 97
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