GENE AND DISEASE: AN ‘‘OMICS’’ AS THE PILLARS OF SYSTEMS MEDICINE
Journal Title: World Journal of Pharmaceutical Research - Year 2019, Vol 8, Issue 5
Abstract
In the age of systems medicine, the pathological set of connections, genetic mutations, allied anomalous pathways, and a response of drug for rectification of the abnormalities/disease are integrated transversely with the human biology systems by employing varied approaches of genomics, epigenomics, transcriptomics, and proteomics technologies. Pharmacogenomics studies the variation in human genome which is employed to predict responses to a specific drug or class of drugs. In recent years with the growth of pharmacogenomics, the concept of personalized medicine has becomes more often accessible in clinic settings for patient care. Most importantly, the rational case for genetics-specific drug selection and dosing is considered more established than the handy list of drugs for which outcomes are demonstrably improved. Thus significant accomplishment is possible with an interdisciplinary approach of genetics, technological and therapeutic measures establishing “OMICS” technologies as the pillars of systems medicine.
Authors and Affiliations
Dr. Aaishwarya Deshmukh
INTERLEUKIN 1 RECEPTOR ANTAGONIST
Interleukins are a group of cytokines that were first seen to be expressed by white blood cells.[1] The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them hav...
CLINICAL ASPECT OF TEMPORAL REGION WSR TO SRUNGATAKA MARMA AS DESCRIBED IN INDIAN SYSTEM OF MEDICINE
From the time immemorial, they were keen in unravelling the secrets of this most sophisticated and complicated machinery. Ayurveda with a broad approach had explained the human body considering its various aspects- metap...
EPIDEMIOLOGY AND MORTALITY OF BURNS IN IMAM ALI AND AL-KINDI TEACHING HOSPITAL IN BAGHDAD/ IRAQ
Background: Despite the progress of the health system, burns remained a problem that cannot be solved or find a way to reduce the complications. All these obstacles are caused by poor health management and lack of financ...
AN OVERVIEW ON EXTRACTION AND PURIFICATION OF FLAVONOIDS FROM MEDICINAL PLANTS
Therapeutic plants gained attention in the current scenario due to their utilization in ethnomedicine for the treatment of a vast number of diseases. This review describes different strategies which have been employed fo...
PREVALENCE OF ANXIETY AND DEPRESSION AMONG AL MADINAH AL MUNAWARAH POPULATION, KINGDOM OF SAUDI ARABIA, 2016/2017
Background: Mental health issues as depression and anxiety have become common issues around the world, and affecting a significant number of populations with multiple negative effects. Objectives: To measure the current...