Gene Frequencies of Haemoglobin Genotype, ABO and Rhesus Blood Groups among Students Population of a Private University in Nigeria-Implications for Blood Banking
Journal Title: SSR Institute of International Journal of Life Sciences (SSR-IIJLS) - Year 2018, Vol 4, Issue 4
Abstract
Background- ABO and Rhesus blood groups are the two most important blood group systems of clinical significance. ABO is classified into four major groups (A, B, AB and O), while Rhesus is classified as positive or negative. Haemoglobin genotype included both normal (HbA) and the variant forms (HbS and HbC), which combined to form six major haemoglobin gene types (HbAA, HbAS, HbAC, HbCC, HbSS and HbSC). Several studied have determined the gene frequencies of haemoglobin genotype, ABO and Rhesus blood groups among different populations with varied patterns. This study was aimed at assessing the gene frequencies of haemoglobin genotype, ABO and Rhesus blood groups among Redeemer’s University students. Methods- This study was a retrospective study which analyzed laboratory data between 2013 and 2017 containing haemoglobin genotype and Rhesus-ABO investigations carried out for newly admitted students. Results- The ABO gene frequencies from this study showed O˃A˃B˃AB; 59.7%, 21.6%, 16.6% and 2.0%, ABO with Rhesus combination showed O+˃A+˃B+˃O-˃AB+˃A-˃B-˃AB- ; 57.1%, 20.8%, 15.9%, 2.6%, 1.8%, 0.8%, 0.7%, and 0.3%. Rhesus positive was found to be far higher than Rhesus negative (Rh+˃Rh-, 95.6%, 4.4%) and haemoglobin genotype distribution showed HbAA˃HbAS˃HbAC˃HbSS˃HbSC˃HbCC; 72.5%, 23.4%, 2.4%, 1.5%, 0.2% and 0.1%. Conclusion- Blood group O, Rhesus positive and haemoglobin AA were found to be more prevalent all through the period under review.
Authors and Affiliations
Onaiwu T. Ohiengbomwan, Nosakhare L. Idemudia, Oloche Owoicho, Aderonke A. Adeyanju
Keywords
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- EP ID EP670980
- DOI 10.21276/ijlssr.2018.4.4.1
- Views 74
- Downloads 0
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