GENES IN SPORT AND DOPING
Journal Title: Biology of Sport - Year 2013, Vol 30, Issue 3
Abstract
Genes control biological processes such as muscle production of energy, mitochondria biogenesis, bone formation erythropoiesis, angiogenesis, vasodilation, neurogenesis, etc. DNA profiling for athletes reveals genetic variations that may be associated with endurance ability, muscle performance and power exercise, tendon susceptibility to injuries and psychological aptitude. Already, over 200 genes relating to physical performance have been identified by several research groups. Athletes’ genotyping is developing as a tool for the formulation of personalized training and nutritional programmes to optimize sport training as well as for the prediction of exercise-related injuries. On the other hand, development of molecular technology and gene therapy creates a risk of non-therapeutic use of cells, genes and genetic elements to improve athletic performance. Therefore, the World Anti-Doping Agency decided to include prohibition of gene doping within their World Anti-Doping Code in 2003. In this review article, we will provide a current overview of genes for use in athletes’ genotyping and gene doping possibilities, including their development and detection techniques.
Authors and Affiliations
Andrzej Pokrywka, Paweł Kaliszewski, Edyta Majorczyk, Agnieszka Zembroń-Łacny
Keywords
Related Articles
- EP ID EP59163
- DOI -
- Views 84
- Downloads 0
Analysis of radiological characteristics distribution in the vertebral bodies of the lumbosacral spine of competitive rowers
Unfavorable biomechanical situations, usually related to the performance of a profession and competitive sports practice, promote formation of overloads. This problem may be particularly perceptible among sportsmen that...
EFFECTS OF CYCLIC STATIC STRETCH ON FATIGUE RECOVERY OF TRICEPS SURAE IN FEMALE BASKETBALL PLAYERS
Static stretch is a safe and feasible method which usually is used before exercise to avoid muscle injury and to improve muscle performance. The purpose of this study was to determine the effects of cyclic static stretch...
Laterality of the lower limbs and carving turns
The aim of this study is to discover whether the lateral preference of the lower limbs influences the execution of successive carving turns or not. Six skilled skiers (men, right lower limb preference, age 26.5±1.61 year...
Nutrition, activity behavior and body constitution in primary school children
Child and adolescent obesity currently affects at least 10-25% of the paediatric population in most developed countries. The BMI value is one of the most appropriate method of defining obesity and has a strong associatio...
Physical activity and mental health: relationships between depressiveness, psychological disorders and physical activity level in women
This research was conducted with an objective to study relationships between physical activity and emotional wellbeing of women. The study involved 659 women aged 18–45. The following questionnaires were used: General He...