Genetic and immunological features of aggressive periodontitis
Journal Title: RSBO - Year 2010, Vol 7, Issue 1
Abstract
Introduction and objective: Aggressive periodontitis intrigues clinicians and researchers due to its rapid progression and its evidences of genetic character. Different theories have tried to explain the individual differences in susceptibility, where genetic and immunological assays have assumed great importance. The purpose of this study was to review the literature in order to comprehend the genetic and immunological features of aggressive periodontitis. Literature review: Articles were examined, specifically the ones dealing with information regarding genetic and/or immunological studies of individuals related to their disease susceptibility.Conclusions: In the presence of dental biofilm, host susceptibility to aggressive periodontitis varies among regions, countries and races. Immune-inflammatory processes that seem to be modified in aggressive periodontitis patients may be transmitted vertically, explaining familial aggregation associated with this disease.
Authors and Affiliations
Miguel MUÑOZ, Rafael BAGGIO, João STEFFENS, Fábio SANTOS, Gibson PILATTI
Keywords
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