Genetic background of osteochondrosis in the horse – a review
Journal Title: Animal Science Papers and Reports - Year 2012, Vol 30, Issue 3
Abstract
Osteochondrosis is considered to be one of the most important problems in European sport horse breeding, as the frequency of OC(D) reaches 25% or more of investigated populations. The present article provides an overview of the genetic background of OC(D) evaluated in different countries. Heritability is low (0.1-0.3) and contemporary selection methods seem not to be sufficiently effective. New approaches regarding molecular methods have been developed and are a promising tool. These include techniques such as whole genome scan, candidate gene analysis and SNP microarrays. Potential candidate genes were found on chromosomes 2, 4, 16, 18, 28 and 30. The most recent results on microarray SNP analysis using 50000 SNP chip detected new QTL regions in the horse genome.
Authors and Affiliations
Dorota Lewczuk, Agnieszka Korwin-Kossakowska
Keywords
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