Genotypes and allele frequencies of angiotensin converting enzyme (ACE) insertion/deletion polymorphism among Omanis
Journal Title: Sultan Qaboos University Medical Journal - Year 2002, Vol 4, Issue 2
Abstract
Objective: To describe the angiotensin converting enzyme (ACE) genotype frequencies among Omani Arabs. Method: A polymerase chain reaction (PCR) test, based on separation of different size DNA fragments, was developed to test the presence or absence (polymorphism) of a small DNA deletion in the ACE gene. The subjects were 124 Omani Arab students of Sultan Qaboos University, Muscat. Results: The frequency of the I allele was 0.29, while that of the D allele was 0.71. The gene frequency distribution did not deviate from Hardy-Weinberg equilibrium. Conclusions: The frequency of D allele among Omanis is similar to that among other Arabs and Africans, but differs significantly from that among the Japanese and Chinese.
Authors and Affiliations
Ali T. Al-Hinai| Departments of Medicine, College of Medicine & H Sc, Sultan Qaboos University, P.O.Box 35, Al-Khod-123, Sultanate of Oman, Mohammed O Hassan| Department of Physiology, College of Medicine & H Sc, Sultan Qaboos University, P.O.Box 35, Al-Khod-123, Sultanate of Oman, Mehmet Simsek| Department of Biochemistry, College of Medicine & H Sc, Sultan Qaboos University, P.O.Box 35, Al-Khod-123, Sultanate of Oman, Hameeda Al-Barwani| Department of Biochemistry, College of Medicine & H Sc, Sultan Qaboos University, P.O.Box 35, Al-Khod-123, Sultanate of Oman, Riad Bayoumi| Department of Biochemistry, College of Medicine & H Sc, Sultan Qaboos University, P.O.Box 35, Al-Khod-123, Sultanate of Oman
Keywords
Related Articles
- EP ID EP13659
- DOI -
- Views 407
- Downloads 18
Contact Lens Induced Corneal Ulcer Management in a Tertiary Eye Unit in Oman - A descriptive study
Te corneal disease is a priority problem in Oman. We present patients with contact lens (CL) induced severe keratitis, admitted in the corneal unit of Al Nahdha Hospital in Oman. Methods: Te study was conducted in 2005-...
Hydrogen Peroxide 3%: Is it Beneficial in Tonsillectomy?
Te world over, tonsillectomy is one of the operations most frequently performed by otolaryngologists, who are in search of a technique of tonsillectomy where the operation time and operative blood loss is reduced. Tis s...
Health Beliefs Related to Diabetes Mellitus Prevention among Adolescents in Saudi Arabia
Objectives: Te incidence of type 2 diabetes mellitus (T2DM) is growing rapidly in the Saudi population. Te purpose of this study was to assess the constructs of the health belief model (HBM) as they relate to T2DM life...
The Pattern of Female Nuptiality in Oman
Objectives: Te purpose of this study was to examine Omani patterns of female nuptiality, including the timing of marriage and determinants of age at a woman’s frst marriage. Methods: Te study utilised data from the 2...
Diffuse Large B-cell Lymphoma, Leg Type A diagnosis not to forget in the elderly