Giant Neurofibroma of Right Cheek
Journal Title: Scholars Journal of Medical Case Reports - Year 2018, Vol 6, Issue 4
Abstract
Abstract: Neurofibroma is a tumor of neural origin derived from the cells that constitute the nerve sheath. It’s an uncommon benign tumor found as a solitary tumor or as a partial manifestation of neurofibromatosis type I (NF1, also called von Recklinghausen’s disease). The cause of solitary neurofibroma is still unknown; it is defined by Marocchio et al. as a hyperplastic hamartomatous malformation rather than neoplastic. NF1 is an autosomal dominant genetic syndrome caused by mutations in genes coding for neurofibromin, it is characterized by cutaneous manifestations as cafe-au-lait spots with a large number of nervous system tumors. The hereditary factors and systemic symptoms present in the disseminated neurofibromas are absent in the solitary type.
Authors and Affiliations
Dr. S Srikanth
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