GINGIVAL ENLARGEMENT INDUCED BY ANTICONVULSANTS, CALCIUM CHANNEL BLOCKERS AND IMMUNOSUPPRESSANTS: A REVIEW
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 7
Abstract
Drug induced gingival enlargement is the term now used to describe medication related gingival hypertrophy or hyperplasia, a condition commonly induced by three main classes of drugs: anticonvulsants, antihypertensive calcium channel blockers and the immunosuppressant cyclosporine. The pathogenesis of drug-induced gingival enlargement is uncertain and there appears to be no unifying hypothesis that links together the three commonly implicated drugs. Various risk factors and etiologic agents like age, drug doses, genetic factors, plaque induced inflammation etc have been proposed. Management of such condition when it interferes with aesthetic, function and occlusion includes non surgical and surgical intervention. It is important that the health practitioner is aware of the potential etiologic agents and characteristic features in order to be able to accurately diagnose and successfully manage such patients.
Authors and Affiliations
Amit Bhardwaj , Shalu Bhardwaj
Keywords
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