Gingival Leiomyosarcoma in a Young Woman Case report and literature review
Journal Title: Sultan Qaboos University Medical Journal - Year 2017, Vol 17, Issue 4
Abstract
Leiomyosarcoma (LMS) is a rare mesenchymal malignancy, of which 3–10% of cases occur in the head and neck region. We report a 22-year-old woman who was referred to the University Hospital of Siena, Italy, in 2016 with an ostensibly benign asymptomatic lump on the mandibular gingiva. Te lesion grew rapidly, causing otalgia in the right ear. An excisional biopsy was performed and primary LMS was diagnosed histologically. Subsequently, the patient underwent radical re-excision of the perilesional mucosa, a partial bone resection and the extraction of four teeth. No recurrences or metastases were detectable at a 20-month follow-up. Tis report discusses the differential diagnosis of LMS with regards to other benign and malignant lesions and reviews the recent literature on primary and secondary oral LMS. Due to its innocuous clinical features—including its asymptomatic nature and presentation at a young age—this aggressive malignancy can go undetected; therefore, an early histopathological diagnosis is crucial.
Authors and Affiliations
Massimo Viviano| Department of Dentistry & Ophthalmology, University of Siena, Siena, Italy, Clelia Miracco| Department of Pathological Anatomy, University of Siena, Siena, Italy, Guido Lorenzini| Department of Medical Biotechnology, University of Siena, Siena, Italy, Gennaro Baldino| Department of Pathological Anatomy, University of Siena, Siena, Italy, Serena Cocca| Department of Ear, Nose & Throat, University of Siena, Siena, Italy
Keywords
Related Articles
- EP ID EP14828
- DOI 10.18295/squmj.2017.17.04.017
- Views 339
- Downloads 14
An Unnoticed Broken Sheathed Metallic Stylet in an Endotracheal Tube A case report
We report a 58-years old patient, who underwent surgery for a fracture to the neck of the femur. Tracheal intubation was performed with the aid of a stylet; however, 15 minutes later, it was brought to the notice of th...
Laparoscopic Repair of Traumatic Intraperitoneal Bladder Rupture
Intraperitoneal rupture of the bladder is an uncommon condition that is usually caused by pelvic fractures. Tis is a true surgical emergency managed conventionally by open laparotomy with single or double layer repair....
Combination of Continuous Dexmedetomidine Infusion with Titrated Ultra-Low-Dose Propofol-Fentanyl for an Awake Craniotomy Case report
An awake craniotomy is a continuously evolving technique used for the resection of brain tumours from the eloquent cortex. We report a 29-year-old male patient who presented to the Khoula Hospital, Muscat, Oman, in 201...
Graves’ Disease following Interferon Therapy for Chronic Hepatitis C Infection
We describe the first case of Graves’ disease occurring at Sultan Qaboos University Hospital, Oman, in a patient who was under treatment with interferon alfa for HCV infection. INF-α is now being widely used to treat...
The Epidemiology of Acute Coronary Syndrome in Oman Results from the Oman-RACE study
Objectives: This study aimed to evaluate the epidemiology and coronary risk factors of acute coronary syndrome (ACS) in Oman. Methods: Data were collected through a prospective, multinational, multicentre survey of con...