Glycated hemoglobin HbA1c, waist circumference, and waist-to-height ratio in overweight and obese adolescents
Journal Title: Paediatrica Indonesiana - Year 2017, Vol 57, Issue 2
Abstract
Background Central obesity has been associated with a high risk of insulin resistance. Waist circumference and waist-to-height ratio are anthropometric indices for determining central obesity and have been associated with increased blood pressure, cholesterol, and insulin levels. In adults, fat distribution around the waist is a valid predictor of glycated hemoglobin (HbA1c)levels, and is currently recommended by experts as a diagnostic tool for diabetes. Central obesity measurement has advantages over fasting blood glucose and oral glucose tolerance tests, as it is simple and inexpensive to perform.Objective To assess for correlations between HbA1c level and waist circumference as well as waist-to-height ratio and to assess factors potentially associated with HbA1c levels in overweight and obese adolescents.Methods This cross-sectional study was done in four junior high schools in Yogyakarta, which were obtained by cluster sampling. Overweight and obese students who were generally healthy were included in the study. Subjects underwent waist circumference and waist-to-height ratio measurements, as well as blood tests for HbA1clevels.Results Sixty-seven children participated in the study, with 48 girls (71.6%) and 19 boys (28.4%). Waist circumference and HbA1c levels were not significantly associated (r=0.178; P=0.15). However, waist-to-height ratio and HbA1c levels had a weak positive correlation (r=0.21; P=0.04). Linear regression analysis revealed that waist-to-height ratio had a significant association with HbA1c level (P=0.02), but age, sex, and nutritional status did not.Conclusion Waist-to-height ratio is correlated with HbA1c levels in overweight and obese adolescents.
Authors and Affiliations
Elysa Safrida, Neti Nurani, Madarina Julia
Keywords
Related Articles
- EP ID EP438201
- DOI 10.14238/pi57.2.2017.57-62
- Views 103
- Downloads 0
Nutritional status of soil-transmitted helminthiasis-infected and uninfected children
Background Soil-transmitted helminth (STH) infections remain a public health problem in developing countries. Their prevalence is particularly high in rural areas with people of low socioeconomic level. A single or mixed...
Red cell distribution width and mortality in pediatric sepsis
Background Red cell distribution width (RDW) is a hematological parameter routinely obtained as part of the complete blood count. Recently, RDW has emerged as a potential independent predictor of clinical outcomes in adu...
Diagnostic value of newborn foot length to predict gestational age
Background Identification of gestational age, especially within 48 hours of birth, is crucial for newborns, as the earlier preterm status is detected, the earlier the child can receive optimal management. Newborn foot l...
Reducing dyspeptic symptoms in children: proton pump inhibitor vs. H2 receptor antagonist
Background Dyspepsia is known as a leading cause of uppergastrointestinal tract morbidity. If left untreated, dyspepsia maybecome chronic. Dyspeptic symptoms manifest as epigastricpain, heartburn, nausea, hematemesis, or...
Tuberculosis risk factors in children with smear-positive tuberculosis adult as household contact
Background Children in household contact of adults with smear-positive tuberculosis (TB) are at higher risk of TB infection. Screening of these children is a main strategy for eliminating childhood TB.Objective To determ...