Glycated hemoglobin in early pregnancy as a predictor of gestational diabetes mellitus
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2018, Vol 5, Issue 3
Abstract
Introduction The prevalence of Gestational diabetes mellitus GDM is high in Asian subcontinent As per current guidelines the routine screening for GDM is at 24 to 28 weeks of gestation30 to 50 of GDM cases may remain undiagnosed until such period of screening This study aims to investigate HbA1C levels at as early as 12 weeks of pregnancy as a predictor of GDMMaterials and Methods This prospective study included 100 patients enrolled at their first antenatal visit or before 12 weeks of gestational age who attended OPD At the time of enrolment for HbA1c and routine antenatal investigations were done A 75 gm GTT was done at 22 to 26 weeks of gestation HbA1c cutoff was taken as 57 64 and patients having value 57 were taken as abnormal Subjects with HbA1c 65 overt diabetes hemoglobinopathies anaemia chronic renal diseases and multiple pregnancies were excluded from the studyResults It is found that women 28 years had higher levels of hbA1C in comparison to patients Conclusion The study concludes that women with higher HbA1c 57 were more likely to develop GDM than those women with lower HbA1C 57 HbA1c can be done routinely in early pregnancy 1st trimester Women with higher HbA1c 57 can benefit from early interventions early in pregnancy thereby prevent GDM and adverse perinatal and pregnancy outcomes Keywords Early pregnancy Glycated hemoglobin GDM Maternal age
Authors and Affiliations
Sujithra. D. , Sukanya Mukherjee, Sudha S
Keywords
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- EP ID EP475128
- DOI 10.18231/2394-2754.2018.0075
- Views 90
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