Gnathic Osteosarcomas- An Institutional Experience Of 10 Cases
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Background: Sarcomas are neoplasms arising from the mesodermal tissue and constitute < 1% of body tumors. Of these,only 5-15% occur in the head and neck region. Among these osteosarcomas are the most common. They are difficult to treat due to their aggressiveness, propensity for recurrence and their proximity to vital anatomical structures. There is no general consensus on the adjuvant modality of management. Methods: 10 patients with head and neck osteosarcoma, surgically treated at our institute from 2000 to 2016 were reviewed retrospectively. Results: Mandible was the most common affected site followed by maxilla. The disease had a male preponderance. Chondroblastictype was the most common histopathological variant in our study group. A multimodality treatment approach was used comprising of neoadjuvant chemotherapy followed by surgery,with or without post op radiotherapy and chemotherapy in the patients. After a median follow-up of 1 yr, around 38 % were alive and disease free. Postoperative adjuvant radiotherapy for local control failed to attain statistical significance. Conclusions: Surgery is the mainstay of the treatment of head and neck osteosarcoma. Adjuvanttherapy ,however ,has doubtful benefit.
Authors and Affiliations
Philip John Kottaram, Deepak Janardhan, Shaji Thomas, Nebu Abraham George, Bipin T Varghese
Keywords
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- EP ID EP595951
- DOI 10.9790/0853-16050198101.
- Views 58
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