Gnathic Osteosarcomas- An Institutional Experience Of 10 Cases
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Background: Sarcomas are neoplasms arising from the mesodermal tissue and constitute < 1% of body tumors. Of these,only 5-15% occur in the head and neck region. Among these osteosarcomas are the most common. They are difficult to treat due to their aggressiveness, propensity for recurrence and their proximity to vital anatomical structures. There is no general consensus on the adjuvant modality of management. Methods: 10 patients with head and neck osteosarcoma, surgically treated at our institute from 2000 to 2016 were reviewed retrospectively. Results: Mandible was the most common affected site followed by maxilla. The disease had a male preponderance. Chondroblastictype was the most common histopathological variant in our study group. A multimodality treatment approach was used comprising of neoadjuvant chemotherapy followed by surgery,with or without post op radiotherapy and chemotherapy in the patients. After a median follow-up of 1 yr, around 38 % were alive and disease free. Postoperative adjuvant radiotherapy for local control failed to attain statistical significance. Conclusions: Surgery is the mainstay of the treatment of head and neck osteosarcoma. Adjuvanttherapy ,however ,has doubtful benefit.
Authors and Affiliations
Philip John Kottaram, Deepak Janardhan, Shaji Thomas, Nebu Abraham George, Bipin T Varghese
Keywords
Related Articles
- EP ID EP595951
- DOI 10.9790/0853-16050198101.
- Views 44
- Downloads 0
A Clinical Analysis of Infections of Deep Neck Space With Respect To Bacteriology and Antibiotic Sensitivity
Deep neck space infection refers to an infection in the potential spaces and fascial planes of the neck, either with abscess formation or cellulitis. This is a prospective study of 40 patients diagnosed and undergoing tr...
Comparison of EndoVac, CanalBrush, EndoActivator and Syringe Irrigation on Removal of Triple Antibiotic Paste
The aim of this study was to compare the efficacy of different irrigation techniques in the removal of triple antibiotic paste (TAP) from root canal walls.Root canal preparations was performed up to size #30 on 46 extrac...
Chemical Structural Alterations of Root Surface After Er: YAG Laser, Nd: YAG Laser Irradiation-An Infrared Spectroscopic Study
AIM: To assess the chemical structural alterations of root surface by using Fourier Transform Infrared Spectroscopy followed by Er: YAG and Nd: YAG laser irradiation. MATERIAL AND METHOD: Fifty five upper incisor teeth e...
Incidence of Ectopic Pregnancies in Tertiary Centre of Jharkhand-A Population Based Cross Sectional Study
ABSTRACT Background- In spite of the tremendous advances in obstetric care and technology, ectopic pregnancy remains an enigma for a women full of dreams of blissful motherhood, as it may turn into a nightmare and a cata...
A Clinical Study of Risk Factors in the Development of Incisional Hernias in Post Laparotomy Patients
The aim of the present study is to comprehensively study and evaluate the risk factors in the development of incisional hernia. Patients and methods: This hospital based prospective study includes100 consecutive casesdia...