Green Preparation of Jasmine Oil Mediated Bovine Serum Albumin Nanodiscs/nanocubes
Journal Title: Scholars Academic Journal of Pharmacy - Year 2016, Vol 5, Issue 1
Abstract
The preparations of various metal and polymeric nanoparticles were under scientific considerations these days to get the controllable geometry of prepared nanostructures with the ease of their smallest size at nanoscale. Many chemically modified nanoparticles such as nanosphere, nanodiscs, nanocubes, nanowires and nanorods are going to be fabricated with many biocompatible and nontoxic biomaterials (carbon nanotubes, chitosan, albumin and lipopolysaccharides and polysaccharides) or metals ions (gold, silver, iron and copper). These fabricated biomaterials and tagged metal ions were found to improve the oxidative etching effect in nanostructures (nanodiscs/nanocubes) that play very important role in manipulation of nanostructure geometry and their analysis. Bovine serum albumin was found to report a biocompatible, easy biodegradable and cost effective matrix for preparing the nanoparticles due to its well known exploitable characteristics e.g. biocompatibility, non-antigen city and non-toxicity. Hence, this study can provide an potential approach of green synthesis to control the shape of biocompatible bovine serum albumin nanodiscs/nanocubes by using jasmine oil as naturally occurring cheap and easily available emulsifier. Characterization of prepared bovine serum albumin was performed by using Scanning Electron Microscopy (SEM) to observe the prepared nanodiscs/nanocubes which had been going to be minimized to the expected size at nanoscale. So, this designed method can be proved a cost effective and green method to prepare non-toxic and biocompatible bovine serum albumin nanostructures to explore further their therapeutic applications being as nonviral gene or drug nanocages to carry out the site specific targeted delivery. Keywords: Bovine serum albumin; Jasmine oil; Nanocubes; Nanodiscs, Scanning Electron Microscopy.
Authors and Affiliations
Dr. Kirti Rani
Keywords
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