Gross Morphological Variation in Preterm Placenta in Gestational Diabetes Mellitus and Pregnancy Induced Hypertension
Journal Title: Journal of Enam Meical College - Year 2011, Vol 1, Issue 2
Abstract
Background: Preterm birth is the primary cause of perinatal mortality and morbidity. Recently, it has become a significant issue in public health policies of developing countries. Among the various causes, pregnancy induced hypertension (PIH) and Gestational diabetes mellitus (GDM) are two important high-risk factors for preterm birth. Again, placenta is a mirror that reflects the well-being of the fetus and continuously undergoes a change in weight, structure, shape and function in order to support the well-being of the fetus. Objective: To make an in-depth analysis on the possible gross morphological changes in preterm placenta in respect of GDM and PIH. Materials and Methods: The study was observational, analytical and cross sectional. The patients under this study were selected from the Obstetric ward of BSMMU and BIRDEM Hospital, from June 2005 to October 2005. A total of sixty-six samples were collected from women during 28 weeks to 36 completed weeks of gestation. Among them, twenty-two samples were from mothers having GDM, twenty-two having PIH and twenty-two belonged to normal pregnancy (control group). The placentas were examined to measure their diameter, thickness, cotyledons number, weight, and volume. Results: In this study, the GDM group showed significantly higher values for the variables of diameter, weight, volume and number of cotyledons as compared to PIH group. On the other hand, the thickness of the placenta showed lower values in GDM group, but the result did not reach a significant level. Conclusion: From the findings of this study, it is difficult to establish a clear-cut correlation about placental changes in diabetic and hypertensive mothers during pregnancy. However, the changes in placental weight, volume and diameter found in gestational diabetic mother may be a long term compensatory mechanism, aiming to secure a sufficient nutrient supply to support the growth of the foetus. So, postnatal examination of the placenta can yield information that may be important for immediate and late management of the mother and neonate.
Authors and Affiliations
Fahima Akhter, Roxana Ferdousi, Rayhana Sultana
Keywords
Related Articles
- EP ID EP36129
- DOI https://doi.org/10.3329/jemc.v1i2.11466
- Views 403
- Downloads 0
From the Desk of Editor-in-Chief Vol 9(1)
Alhamdulillah! We have already completed eight years of publication of Journal of Enam Medical College. This is the 8th anniversary issue of Journal of Enam Medical College. This is a great success and landmark in the...
Exclusive Breastfeeding ─ Practices, Problems and Promises
Exclusive breastfeeding is the best recommended infant feeding method for the frst six months of life and has a protective effect against child morbidity and mortality1, but the reduction in the rate of the EBF is a...
Outcome of Childhood Acute Lymphoblastic Leukaemia after Induction Therapy --- Three-Year Experience in a Tertiary Care Hospital in Bangladesh
Background: The incidence of different malignancies is increasing among the world populations. Acute lymphoblastic leukaemia (ALL) is the most common of all the paediatric malignancies. Response to induction therapy is...
Fight against Suicide
Abstract not available
Evaluation of Recently Developed Regression Equation with Direct Measurement of Low-density Lipoprotein Cholesterol in a Bangladeshi Population
Background: Meaningful underestimation of low-density lipoprotein (LDL) cholesterol is an important shortcoming of Friedewald’s formula (FF) at higher triglyceride (TG) levels. Recently a regression equation (RE) has b...