Group B streptococcus detection in China: comparison of different screening methods and different sampling sites
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2016, Vol 6, Issue 4
Abstract
Objectives: To evaluate the use of real-time polymerase chain reaction (RT-PCR) and bacterial culture methods to detect group B streptococcus (GBS) in Chinese pregnant women in the third trimester; to separately assess the prevalence of rectal and vaginal GBS colonization ; and to determine the antimicrobial susceptibility pattern of the isolates. Methodology: Samples were collected from 505 women at 35 and 37 weeks gestation at the Peking Union Medical College Hospital. Bacterial culture and RT-PCR were performed. Antimicrobial susceptibility to commonly used antibiotics was also analyzed. Results: The overall GBS colonization rate was 7.5%. The colonization rate, sensitivity, and negative predictive value of the bacterial culture method were 2.8%, 36.8%, and 95.1%, respectively, and these values were 7.3%, 97.4%, and 99.8%, respectively, for PCR (p<0.001). The GBS colonization rate of the rectum (6.7%) was higher than that of the vagina (2.8%) (p=0.005). Antimicrobial susceptibility testing showed that 100% were sensitive to penicillin, cephalo-sporin and vancomycin. Conclusions: RT-PCR was found to be a rapid and sensitive test for the detection of GBS colonization in Chinese pregnant women. Rectal swabbing was also important for detecting GBS colonization. β-lactams are the first-line antibiotics used for the treatment of GBS. J Microbiol Infect Dis 2016;6(4): 179-183
Authors and Affiliations
Xi Wang, Yingna Song, Liangkun Ma, Juntao Liu, Yingchun Xu, Jie Yi
Keywords
Related Articles
- EP ID EP412733
- DOI 10.5799/jmid.vi.328930
- Views 76
- Downloads 0
Kompartman sendromuna neden olan deri şarbonu olguları
Bacillus anthracis şarbon hastalığının etkenidir. Şarbon, üç klinik formu bulunan, zoonozdur. Klinik formlar deri, inhalasyon ve gastrointestinal şarbondur. Olguların % 95’ini deri şarbonudur. Hastalık genellikle kendi k...
Antimicrobial Efficacy of Silymarin and Silibinin Against Oral Microorganisms
Objective: To evaluate the antimicrobial effect of silymarin and silibinin, a plant derived flavonoid compounds against oral microorganisms that are responsible for dental caries. Methods: In the current investigation, w...
Mide kanserinde Helicobacter pylori ile DNA hipermetilasyonunun ilişkisi
Mide kanseri (MK) tüm dünyada sık görülen kanserlerden biridir. MK oluşumu genetik ve epigenetik değişikliklerin birikimi ile çok adımlı ilerleme gösterir. Deoksiribonükleik asit (DNA) dizisi değişmeden gen ifadesinde me...
Anthelmintic Activity of Ethanol Extract of Polygonum minus Leaves against Ascaridia galli
Objectives: Helminth infection is one of the main matters that cause health problems in developing countries. Polygonum minus are empirically used as an anthelmintic drug, but there has been no scientific study that prov...
Occupational exposures among healthcare workers: A teaching hospital sample
Objective: Healthcare workers (HCWs) are at risk for occupational injury associated with contaminated blood and body fluids. This study aims to examine the frequency and type of occupational injuries and to determine bes...