Growing Teratoma Syndrome of the Ovary with Neuroendocrine Tumor: A Rare Case Report
Journal Title: Scholars Journal of Medical Case Reports - Year 2018, Vol 6, Issue 10
Abstract
Growing teratoma syndrome (GTS) is a rare complication of the malignant ovarian germ cell tumors characterized by enlarging benign metastatic masses during or after chemotherapy with normalized tumor markers. Benign masses consist of mature teratomatous elements. Surgical excision of the masses remains the mainstay of the treatment. We present a rare case of GTS following an embryonal cell carcinoma of ovary with neuroendocrine tumor arising from the splenic deposit. The patient initially presented 15years ago as a recurrence following embryonal cell carcinoma of ovary operated elsewhere. After secondary cytoreductive surgery followed by chemotherapy, she presented with multiple masses after 11years. Histopathology of the excised masses revealed mature teratoma with neuroendocrine tumor. This case emphasizes the long term follow up needed for prompt recognition of GTS. Also, this case is unique in the finding of a secondary malignancy arising in a GTS of the ovary with only one case reported till date.
Authors and Affiliations
Sravanthi Nuthalapati, Praveen S Rathod, Pallavi V Reddihalli, Usha Amirtham, Uttamchand D Bafna
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