Guidelines for euthanasia of laboratory animals used in biomedical research
Journal Title: Medicamentul Veterinar / Veterinary Drug - Year 2012, Vol 6, Issue 1
Abstract
Laboratory animals are used in several fields of science research, especially in biology, medicine and veterinary medicine. The majority of laboratory animals used in research are experimental models that replace the human body in study regarding pharmacological or biological safety products, studies conducted for a better understanding of oncologic processes, toxicology, genetic studies or even new surgical techniques. Experimental protocols include a stage in which animals are euthanized in order to remove organs and tissues, or for no unnecessary pain and suffering of animals (humane endpoints) or to mark the end of research. The result of euthanasia techniques is a rapid loss of consciousness followed by cardiac arrest, respiratory arrest and disruption of brain activity. Nowadays, the accepted euthanasia techniques can use chemicals (inhalant agents like: carbon dioxide, nitrogen or argon, overdoses of injectable anesthetics) or physical methods (decapitation, cervical spine dislocation, stunning, gunshot, pitching).
Authors and Affiliations
Adina Faur (Baias), Romeo Cristina, Viorica Chiurciu
Keywords
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