Guselkumab as a Possible New Treatment for Psoriasis
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2023, Vol 3, Issue 5
Abstract
Introduction: In Mexico it affects approximately 2 million people, with a significant impact on quality of life and difficult to manage. Theoretical framework:The lesion it causes is round, salmon-pink papules and plaques, located on knees, elbows and scalp. The diagnosis is mainly clinical and the treatment will depend on the affected body surface and the location. The drugs considered first line are topical and second line drugs are used systemically, which in many occasions have adverse effects that make attachment difficult. Guselkumab, a drug approved in 2017, is an IgG1 that blocks the p19 subunit of IL-23.Discussion: Guselkumab, which is a monoclonal antibody, provides better patient outcomes compared to the drugs used in current therapeutics. There is little information currently available on Guselkumab since it has only recently been approved, butin all studies it has shown to be superior to other monoclonal antibodies, the main disadvantage being that it is not currently available in Mexico and the long administration time.Conclusion: Researching new drugs helps us to provide the patient with atreatment with the least amount of adverse effects, achieving greater adherence and better control of the disease.
Authors and Affiliations
Ingrid Pamela Rodríguez Minguela ,María Fernanda Gámez Acosta ,Zuleyka Roxana Martínez Martínez , Edit Cano Muñoz , Alfredo López Gómez ,Nallely Olivera Ruiz , Monserrat Espinosa Ramos
Keywords
Related Articles
- EP ID EP740091
- DOI 10.47191/ijmscrs/v3-i5-04
- Views 50
- Downloads 0
Giant Peritoneal Free Body: Case Report
Free bodies in the peritoneal cavity are solid, very rare and mostly asymptomatic tumors. We present the case of a finding of free body in the peritoneal cavity during appendectomy. Free bodies in the per...
Amoxicillin plus Clavulanic Acid Vs Amoxicillin in the Treatment of Community Acquired Pneumonia in Children: A Double-Blind, Randomized, Controlled Trial
WHO recommendations for the management of Community Acquired Pneumonia (CAP) have been revised since 2014, amoxicillin is recommended as first choice for oral antibiotic therapy in domiciliary treatment of children. This...
Hypothermia: Diagnosis and Treatment
Hypothermia is defined as a so-called central vital sign below 35°C (95°F). Impaired thermoregulation may contributeto accidental hypothermia. Hypothermia is evaluated as mild, moderate,...
Antimicrobial and BiochemicalProperties of Three Nigerian food Spices;Piper guineense, Xylopiaaethiopica and Monodoramyristica
Piper guineense, Xylopiaaethiopica and Monodoramyristicaseeds are among the plant parts commonly used as spices and studied evaluating the proximate composition while mineral parameters were evaluated using...
Endoscopic Treatment of Zenker's Diverticulum. A Review of The Literature
Zenker's diverticulum (ZD) is a sac-like evagination of the mucosa and submucosa through the Killian triangle, an area of muscleweakness between the transverse fibers of the cricopharyngeal muscle and the oblique fibers...