Guselkumab as a Possible New Treatment for Psoriasis
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2023, Vol 3, Issue 5
Abstract
Introduction: In Mexico it affects approximately 2 million people, with a significant impact on quality of life and difficult to manage. Theoretical framework:The lesion it causes is round, salmon-pink papules and plaques, located on knees, elbows and scalp. The diagnosis is mainly clinical and the treatment will depend on the affected body surface and the location. The drugs considered first line are topical and second line drugs are used systemically, which in many occasions have adverse effects that make attachment difficult. Guselkumab, a drug approved in 2017, is an IgG1 that blocks the p19 subunit of IL-23.Discussion: Guselkumab, which is a monoclonal antibody, provides better patient outcomes compared to the drugs used in current therapeutics. There is little information currently available on Guselkumab since it has only recently been approved, butin all studies it has shown to be superior to other monoclonal antibodies, the main disadvantage being that it is not currently available in Mexico and the long administration time.Conclusion: Researching new drugs helps us to provide the patient with atreatment with the least amount of adverse effects, achieving greater adherence and better control of the disease.
Authors and Affiliations
Ingrid Pamela Rodríguez Minguela ,María Fernanda Gámez Acosta ,Zuleyka Roxana Martínez Martínez , Edit Cano Muñoz , Alfredo López Gómez ,Nallely Olivera Ruiz , Monserrat Espinosa Ramos
Keywords
Related Articles
- EP ID EP740091
- DOI 10.47191/ijmscrs/v3-i5-04
- Views 35
- Downloads 0
The Study on the Typology of Kenyang Diet and Low-Energy Diet on Obesity Therapy
This study examines the characteristics and composition of macro and micronutrients in kenyang diet in obesity therapy compared with a regular obesity diet, a low-energy diet. The approach is qualitative, Diet Quality...
Correlation between Plica Mediopatellar Damages and Cartilage Lesions on Arthroscopic Findings of the Knee
Introduction: The mediopatellarplica are folds in the synovium that represent the embryological remnant in the development of the synovial cavity of the knee. Our study aim to investigate the damage to the me...
Acute Small Bowel Obstruction
An intestinal obstruction can be divided into mechanical or functional of the small intestine or the large intestine. This can happen if the lumen of the intestine is partially or completely blocked. Within the common cl...
Diagnosis and Treatment of Pyelonephritis During Pregnancy
Urinary tract infections are the most common infections in pregnant women. The most common are asymptomatic bacteriuria, cystitis and pyelonephritis, the latter presenting as a complication in 1 to 2% of women. Urolith...
Covid -19 Pandemic Disease
Covid-19 is one of the pandemic diseaseswhich was widely spread all over the world. Nowthe new mutated variant strain, Deltaplus, may cause a third wave of thecoronavirus.So,allof themare worried about...