H1N1 AND MOLECULAR DIAGNOSIS- RAPID AND EASE IN VIRAL AND DISEASE MONITORING
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2013, Vol 2, Issue 3
Abstract
Influenza a viruses are medically significant pathogens responsible for higher mortality and morbidity throughoutthe world. Swine influenza known to be caused by influenza A subtypes H1N1, H1N2, H2N3,H3N1, and H3N2, is ahighly contagious and an economically important disease of pigs caused by type A influenza viruses of the familyOrthomyxoviridae. Mainly H1N1, H1N2, H3N2 and H3N1 subtypes of influenza A viruses are endemic in pigpopulations worldwide. Pigs can also be infected by humans and avian influenza viruses and, acts as ‘mixingvessels’ for them, giving rise to novel reassortants. Human infections with swine flu H1N1 viruses have beenearlier reported to be rare. Current review focuses on the significant approach of the usage of Molecular methodutilizing Real-Time PCR in detail for the detection of type A influenza virus (H1N1 subtype) in human specimens.
Authors and Affiliations
Narotam Sharma*| Molecular Research Laboratory, Department of Biochemistry, Shri Guru Ram Rai Institute of Medical & Health Sciences, Patel Nagar, Dehradun, Uttarakhand, India., Mukesh Kumar| Molecular Research Laboratory, Department of Biochemistry, Shri Guru Ram Rai Institute of Medical & Health Sciences, Patel Nagar, Dehradun, Uttarakhand, India., Brijesh Sharma| Mangalayatan University, Beswan, Aligarh, U.P., India., Rinki Goel| Molecular Research Laboratory, Department of Biochemistry, Shri Guru Ram Rai Institute of Medical & Health Sciences, Patel Nagar, Dehradun, Uttarakhand, India., Shayan Ghosh| Molecular Research Laboratory, Department of Biochemistry, Shri Guru Ram Rai Institute of Medical & Health Sciences, Patel Nagar, Dehradun, Uttarakhand, India., Manitosh Pandey| Jiwaji University, Gwalior, M.P., India., Surbhi Sharma| Molecular Research Laboratory, Department of Biochemistry, Shri Guru Ram Rai Institute of Medical & Health Sciences, Patel Nagar, Dehradun, Uttarakhand, India.
Keywords
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