Haematogical problems in pregnant women at a general practitioner’s practice
Journal Title: Postępy Nauk Medycznych - Year 2010, Vol 23, Issue 5
Abstract
In normal pregnancy there are changes in a peripheral blood and coagulation and fibrinolysis systems. Of these, the most important are physiological dilutional anaemia, benign neutrophilic leucocytosis, benign thrombocytopenia, coagulation activation and fibrinolysis inhibition. A general practitioner must be familiar with these changes to diagnose correctly anaemia and thrombocytopenia, the two most common haematological abnormalities in pregnancy. As a criterion for anaemia in pregnancy, haemoglobin of < 11,0 g/dL in the first and third trimester, and < 10,5 g/dL in the second trimester, and < 10,0 g/dL after parturition are commonly used. Anaemia in pregnant women is mainly due to iron deficiency, an acute blood loss in the puerperium, and infrequently folate deficiency. Given increased alimentary iron absorption, oral iron supplementation is the most convenient, but its poor tolerance may be a problem. However, parenteral iron brings about a faster response. An availability of more and more safe iron complexes with sucrose and carboxymaltose allowed to use easier intravenous iron in pregnancy, practically even in moderate iron deficiency anaemia with haemoglobin of < 10 g/dL in the second and third trimester and the puerperium. Of thrombocytopenias in pregnancy, the most common is benign incidental thrombocytopenia, then thrombocytopenia associated with hypertensive complications of pregnancy and immunologic thrombocytopenia, which account for 74%, 21% and 4% of cases, respectively. Platelet count of < 100 x 109/L is a quantitative criterion for diagnosing immunologic thrombocytopenia. Besides anaemia and thrombocytopenia, we also consider thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, congenital disorders of plasma coagulation, and myeloproliferative neoplasm.
Authors and Affiliations
Tomasz Sikorski, Ewa Marcinowska-Suchowierska
Keywords
Related Articles
- EP ID EP53903
- DOI -
- Views 137
- Downloads 0
Wytwarzanie biofilmu przez metycylino-oporne szczepy Staphylococcus aureus
Wstęp. Jednym z najczęstszych czynników zakażeń skóry i tkanek miękkich są szczepy Staphylococcus aureus. Wśród nich najbardziej niebezpieczne i trudne w procesie terapii pacjentów są szczepy metycylino-oporne (MRSA). Wł...
Treatment of femoral neck fractures in elderly patients
Femoral neck fractures have always been a great challenge for an orthopedic surgeon, a personal problem for the patient and his family, furthermore they are associated with high financial and social costs. The frequency...
DNA and RNA analyses in detection of genetic predisposition to cancer
During the past decade many new molecular methods for DNA and RNA analysis have emerged. The most popular in the past like SSCP, HET, CMC, DGGE, RFLP or ASA have been replaced by methods which allowed more cost effective...
Management of esophageal varices bleeding
Esophageal variceal bleeding is the most severe complication of portal hypertension. In most cases portal hypertension results from chronic hepatitis of different etiology or is an innate sequela of liver cirrhosis. In t...
Niedożywienie i zaburzenia odżywiania u kobiet w wieku prokreacyjnym
Niedożywienie kobiet planujących macierzyństwo oraz kobiet ciężarnych stwarza ryzyko nieprawidłowego przebiegu ciąży i gorszego stanu zdrowia dziecka. W Polsce brak jest danych odnośnie częstości występowania niedożywien...