Haematological Parameters in Female Breast Cancer Patients in South Western Nigeria
Journal Title: International Journal of Medical and Health Sciences - Year 2013, Vol 2, Issue 4
Abstract
This is a cross sectional study of age and variations of Haematological parameters among female breast cancer patients and apparently healthy individuals in South western Nigeria.. Eighty eight breast cancer patients from Ladoke Akintola University Teaching Hospital and Abake Medical centre in Osogbo, Osun State were studied between July and November, 2011. Questionnaires for bio data were administered to both the patients (cases) and control subjects. Haematological parameters were run on the EDTA samples for packed cell volume (PCV), white cell count (WBC), red cell indices (MCV, MCH, MCHC), RBC count, platelet count, using automated machine (Sysmex KX-21N, Kobe Japan 2003). Erythrocyte sedimentation rate (ESR) was also performed on the sodium citrate samples using the Western green method. Significant differences (p < 0.05) were seen in the values for WBC, RBC, HB, PCV but not for ESR (p >0.05) among controls below and above age 40 years. The HB, PCV, RBC and WBC and the absolute platelet count were lower in patients compared to the controls with statistically significant differences (p<0.05). However, the mean ESR value significantly higher than the control subjects (p < 0.05). This study has shown that age, anaemia; leucopenia and thrombocytopenia were common basic features to be considered in breast cancer patients and erythropoiesis-related parameters are lower in the older patients.
Authors and Affiliations
Akanni Emmanuel Olufemi, Oguntola Adetunji Saliu, Adeoti Moses Layiwola, Agodirin Sulaiman Olayide
Keywords
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