Haemostatic efficacy: Exploration of Azadirachta indica Bark
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 10
Abstract
The haemostatic potential of alcoholic extracts of Azadirachta indica bark has been evaluated systematically. An attempt has been made to elucidate the modes of action of the cold and hot alcoholic extracts, using platelet aggregation test, prothrombin time test, activated partial thromboplastin time test and whole blood clotting for a range of concentrations. HPTLC fingerprint of alcoholic bark extract has been obtained as a quality control parameter. Presence of tannins and saponins in the extract of bark has been confirmed by HPTLC profiling. These metabolites are known to help in clot formation. The study indicates that alcoholic bark extract of Azadirachta indica can be used effectively as an excellent topical haemostatic agent.
Authors and Affiliations
Janhavi A. Bhagwat
Keywords
Related Articles
- EP ID EP202801
- DOI -
- Views 88
- Downloads 0
Trabeculectomy with ologen implant versus trabeculectomy with mitomycin-C in primary open angle glaucoma: A 2-year study
Aim: The aim of this study is to assess the efficacy and safety of trabeculectomy with Ologen implant versus trabeculectomy using Mitomycin-C (MMC) in patients of open-angle glaucoma. Study design- Hospital based, prospe...
Mouth Dissolving Tablets- A Review
Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded to be safe, economical, easy to form and the most important is the patient compliance. Other various dosage forms are also...
An introduction to Diabetic Neuropathy: A Review
Diabetic neuropathy is the most frequent and devastating complication of diabetes mellitus leading to great morbidity and mortality, resulting in a massive financial burden for diabetes care. The prevalence of diabetic n...
Analytical method development and validation of teneligliptin hydrobromide in pure form by HPLC
A Simple, rapid, sensitive, precise and cost effective High-performance liquid chromatographic (HPLC) method was developed for the Teneligliptin Hydrobromide in pharmaceutical dosage form. The separation was carried out...
Personality factors and Coping Skills among Coronary Heart Disease Patients
Coronary heart disease is a leading cause of death and a cause of disability worldwide. Personality factors and coping skills are important determinants of morbidity and mortality associated with Coronary artery disease....