Hashimoto Thyroiditis-Association with Eosinophilic Infiltration in FNAC
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 10
Abstract
Objective: To assess whether an eosinophilic infiltration of the thyroid gland has a higher association with diffuse thyroid swellings especially Hashimoto's thyroiditis and search for more cytological clues to increase the sensitivity of diagnosis of diffuse swellings of thyroid gland on Fine needle aspiration cytology (FNAC). Methods: A total of 80 cases were studied. Aspirates from these cases were studied for cytomorphological features, all the cases were divided into two groups- cases and control. The cases diagnosed as Hashimoto's thyroiditis were included in the case group and cases diagnosed as other benign swellings except Hashimoto's thyroiditis were included in the control group.. Results: 40% of the cases showed an average of more than I esinophil per HPF but none of the cases in the control group showed an average more than 1. Thus, WE saw that number of Eosinophils per HPF in the smears diagnosed as Hashimoto's thyroiditis found higher than in the smears from the control group. We also observed that the average ratio of eosinophils to neutrophils in the smears diagnosed as Hashimoto's thyroiditis was found to be significantly greater than in smears from the control group. Among the patients with Hashimoto's thyroiditis 80-90% have high titers of antithyroglobulin antibodies. Conclusion: Besides serological diagnosis presence of eosinophil per HPF increases the sensitivity of cytological diagnosis of Hashimoto thyroiditis.
Authors and Affiliations
Dr Maaz Farooqui
Keywords
Related Articles
- EP ID EP511593
- DOI -
- Views 94
- Downloads 0
Prevalence of Hypomagnesemia and Hypocalcemia on Day one and Day Four in Neonates Born in A Tertiary Care Hospital of Western Maharashtra
Introduction: Hypocalcemia is a frequently observed clinical and laboratory abnormality in neonates. Magnesium and calcium metabolism are closely related. The intestinal absorption and the renal excretion of the two ions...
Study on ECG Changes in Chronic hypertensive Patients in a Medical College Hospital of Odisha
Aims: Aim of this study was to analyze and compare the variations and abnormalities in ECG wave forms among people with chronic hypertension and controls. Methods: The study was conducted in Hi-Tech Medical College & Hos...
Intra Operative Cytological Examination as a Diagnostic Tool for Carcinoma Breast Comparing With Frozen Section
Introduction: Intra operative cytology and frozen section in carcinoma breast Materials and Method: FNAC proven surgical specimens of breast malignancies form the Department of surgery during the period 3years. Total of...
Children with Severe Acute Malnutrition, Outcome and its Complications in Children admitted at tertiary level Centre (MTC) –A Prospective Study
The present study was conducted in malnutrition treatment centre (MTC) at the department of paediatrics, Govt. Medical College, Kota for a period of one year from November 2012 to October 2013. A total of 54 (27 Male and...
A Comparative Analysis of Results of Suspensory Femoral Fixation and Interference Screw Femoral Fixation in Arthroscopic Anatomical Anterior Cruciate Ligament Reconstruction with Quadruple Hamstring Graft
Background: Arthroscopic anterior cruciate ligament reconstruction is the most commonly performed arthroscopic procedure performed worldwide. Material and Methods: Patients operated between January 2013 to February 2014w...