Hearing impairment in patients with Chronic Renal Failure
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 2
Abstract
A number of anatomical, physiological, immunological, pharmacological and pathological similarities exist between the kidney and the cochlea [1]. Active transport of fluid and electrolytes by striae vascularis and the glomeruli suggest that both cochlea and kidney have similar physiological mechanisms [2]. Gradual and progressive destruction of nephrons leads to reduction in glomerular filtration rate eventually leading to increase in blood urea and serum creatinine, electrolyte imbalance, toxic accumulation, metabolic acidosis and disturbances of calcium metabolism. These patients are prone for bleeding diathesis, deranged calcium metabolism, hearing loss and neuropathy [3]. It is widely acknowledged that the inner hair cells of the cochlea are at risk to be damaged by a variety of metabolic, electrolytic and hormonal imbalances.
Authors and Affiliations
Sabena Kaipanikal Thankam Sam
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