Hearing organ function in children with nephrotic syndrome in the course of primary glomerulopathy
Journal Title: Otolaryngologia Polska - Year 2008, Vol 62, Issue 2
Abstract
Nephrotic syndrome (NS) is connected with an increase of glomeral permeability. It generates numerous, reversible electrolic and biochemical disturbances. The aim of the work was complex evaluation of hearing organ in children in the course of NS. Material. 28 children aged from 7 to 17 years suffering from primary glomerulopathy, without renal failure and 28 healthy children in the relative age (control group). Method. In children with NS hearing tests (pure tone audiometry, impedance audiometry, BAEP, DPOAE) have been performed twice: in acute phase and in non-symptomic phase. Such parameters as total protein, albumines, globulins, cholesterol, sodium, potassium, calcium, magnesium were evaluated. Results. In oedematous stage the concentration of total protein, albumines and calcium were signifi cantly decreased and the concentration of cholesterol was increased. Children with NS presented much worse hearing than healthy subjects, even after the symptoms dissapeared. in acute phase such parameters of BAEP as peak III latency and interpeak I-III interlatency were elongated and DPOAE values were decreased. In normal phase BAEP parameters were similar to those in normal group but DPOAE parameters were still much worse than in healthy children. Some of the biochemical parameters correlated with hearing results in children with NS. Conclussions. Hearing organ in children with NS in the course of chronic glomerulopathy is signifi cantly worse than in healthy children. It is probably connected with repeated biochemical and electrolytic disturbances that cause partly reversible alterations in the cochlea, acoustic nerve and brain stem. It may be also caused by ototoxic drugs.
Authors and Affiliations
Krystyna Orendorz-Frączkowska, Anna Medyńska, Agnieszka Jabłonka, Wojciech Gawron
Keywords
Related Articles
- EP ID EP51450
- DOI -
- Views 118
- Downloads 0
The use of VHIT (Videonystagmography Head Impulse Test) in the diagnostics of semicircular canal injuries
Introduction: The aim of that work was to evaluate the usefulness of VHIT (Videonystagmography Head Impulse Test) in the diagnostics of injuries to the semicircular canals. Material and methods: The tests covered 58 pati...
In the case of “difficult” tracheostomy
Difficulties from open surgical procedures are common. The severity and frequency of these occurences depends on several factors: anatomic, physiologic, kind of local patology and skills and experience of operator. The i...
Assessment of cortical auditory evoked potentials in children with specific language impairment
The proper course of speech development heavily influences the cognitive and personal development of children. It is a condition for achieving preschool and school successes – it facilitates socializing and expressing fe...
Analiza czułości i swoistości ogólnopolskiego „Programu przesiewowych badań słuchu u noworodków”
Introduction. Polish National Universal Hearing Screening Program (PNPUHS) has got three-level structure. Audiology Outpatient Clinic in The Childrens’ Memoriał Health Institute in Warsaw is a center of the second and th...
Recurrence in operated patients with laryngeal squamous cell carcinoma
Purpose: The aim of the present study was to investigate the recurrence prevalence in patients with laryngeal squamous cell carcinoma (LSCC) underwent surgery as primary treatment. Material: The assessed group consisted...