Heart Disease in Pregnancy-Evaluation of Spectrum, Association of Predictors with Obstetric Outcome and Need for Comprehensive Medical Care
Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 1
Abstract
ABSTRACT Introduction: Cardiac disorders of varying severity complicate nearly 1% of pregnancies and are an important cause of maternal morbidity and mortality. It is important to define the risk stratification of women with heart disease for optimal prepregnancy counselling and obstetric management. Aim: To study the spectrum of heart disease in pregnancy, identification of various predictors of feto-maternal complications and comparison of the obstetric outcome in women with heart disease who received Comprehensive Medical Care (CMC) beginning at ≤28 weeks, with those who began Antenatal Care (ANC) supervision after 28 weeks. Materials and Methods: A prospective observational study was conducted in the Department of Obstetrics and Gynaecology in Safdarjung Hospital (SJH), New Delhi, India, from October 2014 to March 2016. Pregnant women with heart disease attending the OPD/or delivering in labour room were scrutinised through the eligibility criteria. Out of the 66 eligible women, beginning antenatal supervision at ≤28 weeks of gestation were designated as Group A (n=32) who received CMC. Remaining women (n=34), who supervised after 28 weeks in the hospital for further management were designated as Group B. Analysis was done after applying appropriate tests: t-test, Chi-square test and univariate analysis, as applicable. Results: Incidence of heart disease was 0.35% (71/21,000), out of which Rheumatic Heart Disease (RHD) was predominant. Left heart obstruction was the most common (29/66) predictor for adverse maternal cardiovascular and neonatal event, followed by baseline New York Heart Association (NYHA) Class>II (22/66). Cardiac complications were 2.4 times higher and cardiac mortality was ~3 times more in Group B as compared to Group A. Neonatal mortality occurred in 5.6% (2/36) women in Group B. Conclusion: All pregnant women with heart disease should receive comprehensive multidisciplinary prenatal care. Early ANC supervision and extra prenatal surveillance is recommended according to pregnancy associated risk status. Women with ≥1 predictor of cardiac and neonatal events should be referred to a tertiary care centre for CMC.
Authors and Affiliations
REENU KANWAR, MANJULA SHARMA, SHEEBA MARWAH, PRATIMA MITTAL, NIKITA KUMARI
Attitude of Patients towards Euthanasia Attending Neurology Clinic: A Pilot Study in Iran
ABSTRACT Introduction: Due to the recent progress in medical and technological knowledge, the attitude towards death has changed. Euthanasia is another concept that has acquired attention in the recent decades. Aim: To c...
Colour Change and Surface Gloss of Unpolished Infiltrated Bovine Enamel Submitted to Toothbrushing, pH Cycling and Artificial Ageing
ABSTRACT Introduction: The first clinical sign of a caries lesion which represents mineral loss from the enamel subsurface is white spot lesion. Thus, the use of a resin infiltrant has been cited as a promising treatment...
Bilateral Radicular Dens Invaginatus in Mandibular First Premolars-Report of Two Rare Cases
ABSTRACT Dens invaginatus is a developmental dental anomaly which is clinically seen as a furrow on the palatal aspect of the tooth either limiting to the coronal pulp or extending to the radicular apex. It occurs most c...
Comparative Evaluation of Antimicrobial Efficacy of Chlorhexidine, MTAD and Chitosan as Root Canal Irrigant against Enterococcus faecalis
ABSTRACT Introduction: Endodontic irrigants play a role in disinfection of root canal. Inspite of wider options on selection of irrigant, there is always a search on ideal antibacterial irrigant against recurrent infecti...
Nucleic Acid Amplification Testing Detects HIV Transmission Risk in Serologically-Tested Blood Donor Units
ABSTRACT Introduction: Blood transfusion is an essential life-saving intervention in the healthcare delivery. Mandatory screening of donor units helps prevent transfusion-transmissible infections, such as Human Immunodef...