Helicobacter pylori Infection and Hematologic Disorders: what do We Really Know?
Journal Title: Archives of Clinical Gastroenterology - Year 2015, Vol 1, Issue 1
Abstract
One of the most important events on gastroenterology certainly was the isolation of Helicobacter pylori (H. pylori) by Barry Marshall and Robin Warren in 1983 [1], occurrence which redirected our understanding of the pathophysiology of gastrointestinal diseases. The production of urease as well as the mobility of these bacteria promoted by flagella were identified as essential factors for colonization of the gastric epithelium and, from there, within a few years, the list of H. pylori virulence factors for colonizing and persisting on the gastric surface epithelium besides some factors damaging the mucosa expanded greatly.
Authors and Affiliations
Roesler Bruna Maria
Pancreaticojejunostomy versus pancreaticogastrostomy after pancreaticoduodenectomy to prevent post-operative pancreatic fistula, a dissonance between evidence and practice
Leakage of pancreatic enzymes leading to either formation of abdominal collection or pancreatic fistula is one the most feared complications after pancreaticoduodenectomy. Owing to high morbidity and cost related to panc...
Surgically curable Pancreas Enigma: Solid Pseudopapillary Tumor. Report of a case and literature review
Solid pseudopapillary tumor (SPT) is a rare pancreatic neoplasm, classified as low-grade malignant tumor by the World Health Organization in 2000. Surgical treatment usually provide curative intent. Here in we report a 3...
Portal vein septic thrombosis secondary to complicated appendicitis: Case report
Background: Portal vein septic thrombophlebitis is a rare and serious event of late diagnosis and secondary to intra-abdominal infection. Case report: A 21-year-old man was admitted to the hospital with loss of weight,...
Flies to Humans - Humans to Flies: A Virtuous Circle of Colorectal Cancer Prevention
The two Nobel prizes in physiology or medicine of 1995 and 2011 establish Drosophila genetics as a significant contributor of genes and signaling pathways relevant to human disease, including innate immunity and cancer....
Amyloidosis in colon presenting with rectal bleeding in multipl myeloma: A Case Report
Multiple myeloma (MM) is a malignant proliferation of plasma cells that secrete monoclonal immunglobin (M protein). It accounts for 1% of all cancers and 10% of hematological malignancies. Mean age at diagnosis is 66 yea...