Helicobacter Pylorieradication treatment effects on platelet values in the refractory ITP Splenectomy patients
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH - Year 2016, Vol 8, Issue 6
Abstract
Background and Aims: Idiopathic thrombocytopenic purpura (ITP) is an autoimmune blood disorder with a characteristic purpuric rash and thrombocytopenia. The disease can progress into chronic ITP when steroid treatment fails. A quarter of patients who had splenectomy due to chronic ITP may continue to have thrombocytopenia. In these cases, it is thought that testing positive for H. pylori may be perpetuating thrombocytopenia. Methods: We investigated the presence of H. pylori infection in patients with chronic ITP who are either responsive or refractory to splenectomy using invasive GI endoscopy followed by rapid urease test. Results: We report that chronic ITP patients who were refractory to splenectomy had improved platelet counts following the eradication of H. pylori Conclusions: We suggest screening for H. pylori in patients with chronic ITP refractory to splenectomy. Treatment of H. pylori can increase the response to splenectomy as judged by the increased platelet counts.
Authors and Affiliations
Ahmet ERKEK,, Esra TURAN ERKEK, Sertaç Ata GÜLER
Keywords
Related Articles
- EP ID EP405198
- DOI -
- Views 118
- Downloads 0
Need for prophylactic antibiotic cover for invasive dental procedures in patients on biologic therapy
Biologics are a novel category of drugs which are a solution to modern medicine's problems. They are derived from human genes and are genetically engineered proteins. Biological therapy is shown to be effective in neopla...
Stability of intramuscular injection of Ertapenem combined with Lidocaine stored in polyethylene syringes at 4 ºC and -20ºC
Ertapenem is beta-lactam-type antibiotic with an exceptionally broad spectrum of activity, demonstrating broad-spectrum antimicrobial activity against many Gram-positive and -negative aerobes and anaerobes and is resista...
Learning styles assessment: preferences in medical and dental students using fleming’s vark questionnaire
Introduction: The term, ‘learning style’ describes an individual’s preferred method of gathering, processing, interpreting, organizing and analyzing the information. Learning style is the way in which students begin to f...
Psychosocial experiences of podoconiosis patients’ the case of wolaitta zone
The main purpose of this study was to assess the psychosocial experiences of Podoconiosis patients. To this end, the study examined the psychosocial experiences of 120 Podoconiosis patients, of which 12 purposively selec...
Prevalence and factors associated with workplace violence against health workers in tertiary hospitals in Sokoto, Nigeria
Background: Workplace violence poses global health threats, endangering everyone in their places of work which is considered a public health hazard. Particularly in developing countries, assaults in the workplace results...