Hematological changes in Visceral Leishmaniasis

Abstract

Visceral Leshmaniais (VL) is caused by Leshmania donovani, and is transmitted by the bite of female phlebotomine sandfly. This disease is widely prevalent in the world, and is endemic in a few states of India. Clinical features of this disease include fever, anemia, weight loss, lymphadenopathy, hepatosplenomegaly. Hematological features in VL include anemia, neutropia, lymphocytosis and thrombocytopenia. Bone marrow examination shows reticulo- endothelial cell hyperplasia, erythroid hyperplasia, reduction of neutrophils, eosinophic myelocytes and plasma cells. The ratio of granulocytes to non- granulocytes is decreased. The ability of megakaryocyes to form platelets is also decreased.

Authors and Affiliations

*N. S. Neki, **Jaswinder Singh

Keywords

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  • EP ID EP569115
  • DOI 10.22192/ijcrms.2017.03.06.005
  • Views 148
  • Downloads 0

How To Cite

*N. S. Neki, **Jaswinder Singh (2017). Hematological changes in Visceral Leishmaniasis. INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES, 3(6), 36-40. https://europub.co.uk/articles/-A-569115