Hemoglobin D Disease: An Atypical Presentation
Journal Title: Harsukh Educational Charitable Society International Journal of Community Health and Medical Research - Year 2018, Vol 4, Issue 4
Abstract
Haemoglobinopathies are characterised by structurally abnormal haemoglobin variants of the normal adult haemoglobin (HbA) which led to increase hemolysis and dependency on blood transfusion for maintaining normal range hemoglobin. HbD is characterized by point mutation of Glu→Gln substitution at codon 121 with a GAA→CAA change at the DNA level on chromosome number 11.
Authors and Affiliations
Rai S, Sethi G, Kaur K
Keywords
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