Hemophagocytic lymphohistocytosis presenting as septic shock in a neonate
Journal Title: Journal Of Pediatric Critical Care - Year 2017, Vol 4, Issue 3
Abstract
hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease that usually occurs in infants and young children. It is characterized by severe hyper inflammation due to uncontrolled proliferation of activated lymphocytes and monocytes which are morphologically normal cells. This can lead to production and release of immense number of cytokines referred to as cytokine storm. It is typically a systemic disease with multiorgan involvement. Here we report a case of HLH in a twenty-eight days old baby presenting a clinical picture of septic shock, persistent metabolic acidosis multiple organ failure and disseminated intravascular coagulation (DIC).
Authors and Affiliations
Mary Jacqueline Saviour, Praveen Khilnani
Keywords
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- EP ID EP336165
- DOI 10.21304/2017.0403.00202
- Views 85
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