Hemorrhagic Fever Viruses
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2016, Vol 2, Issue 1
Abstract
Viruses causing hemorrhagic fever are broadly classified into five families as Arenaviridae, Bunyaviridae, Filoviridae, Flaviviridae & Rhabdoviridae. Some of them like Ebola virus can spread through aerosols and are considered aspotentialbioweapons. Most of them have reservoirs or amplifying hosts like rodents. Some of them are tick-borne and maintain tick-mammal- tick cycle while others like dengue & yellow fever are mosquito borne. Human to human transmission has also been reported for some viruses.Those infected manifest with viral prodorme initially & have characteristic hemorrhagic manifestations during the first or second week of illness. They present with leukopenia, deranged coagulation profile and altered liver enzymes. Vaccines are available for a few viruses & ribavirin shows promising results in some cases. Extensive research is being carried for newer therapies for these hemorrhagic fevers which present with periodic epidemics. Prevention of the disease is possible through arthropod control, mosquito nets, barrier nursing & avoidance of close contact with infected people.
Authors and Affiliations
Rabindran Rabindran
Keywords
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