HemosideroticFibrolipomatous Tumor or Pleomorphic HyalinizingAngiectatic Tumor of Soft Parts?: Cytology and Histology of an Unusual Tumor
Journal Title: Saudi Journal of Pathology and Microbiology - Year 2017, Vol 2, Issue 9
Abstract
Abstract:HemosideroticFibrolipomatous Tumor (HFLT) and pleomorphic hyalinizingangiectatic tumor of soft parts (PHAT) are rare, locally aggressive neoplasms with overlapping morphological and immunohistochemical features. HFLT is a recently described neoplasm whose cytological features have not been widely described in the literature. We present the cytological and histopathological features of this case because of its rarity and the intermediate features exhibited in this tumor, suggesting a continuous spectrum of tumors of uncertain differentiation, which includes both HFLT and PHAT. A 29 year old female presented with a painful swelling over the dorsum of foot for 1½ months. FNA of the swelling showed features of a spindle cell neoplasm with marked pleomorphism, cytoplasmic pigment, intranuclear and intracytoplasmic inclusions. A possibility of a sarcoma was given. Histopathological examination of the excised specimen showed features in favor of a soft tissue tumor of intermediate malignancy of uncertain type. Immunohistochemistry showed immunoreactivity for CD34 and negativity for CD31, S-100, HMB-45, Melan-A and pancytokeratin. These findings favoured the possibility of a HFLT. An early PHAT was also considered owing to considerable overlap seen in these two tumors. Keywords:CD34, cytoplasmic pigment, hemosideroticfibrolipomatous tumor(HFLT), intranuclear inclusions, pleomorphic hyalinizingangiectatic tumor of soft parts(PHAT), spindle cell tumor
Authors and Affiliations
NigarFathima M, Meenakshi Swain, Tejal Modi, SVN Anuradha
Keywords
Related Articles
- EP ID EP386258
- DOI -
- Views 69
- Downloads 0
An Ovarian Tumor Like No Other
Mixed ovarian tumors are rare. The association of a granulosa tumor with a mucinous adenocarcinoma is exceptional and has never been reported to our knowledge in the literature. We report the case of a 44 year old patien...
Predominance of Staphylococcus and Staphylococcusaureus Susceptibility to Antibiotics in Men with Urethral Discharge in Benin
Abstract:Antimicrobial resistance became a growing public health problem in the world and sexually transmitted infections (STIs) are one of the five types of pathologies which special care should be given. Staphylococcus...
The Study of Antimicrobial Activity of Partially Purified Ethylacetate Extracts of Bridelia ferrugineaon Clinical Isolates
Abstract: Brideliaferruginea is commonly grown in Western Tropical Africa. The purpose of this research work is to determine the antimicrobial activities, qualitative and quantitative phytochemical screening, elemental c...
A Comparative Study of Conventional and Automated Culture System [BACTEC] For Detection of Bacterial Infection
Isolation of microorganisms is very important for accurate treatment and is one of the important concerns for clinical microbiologists. The accuracy and rapidity of treatment are critical for successful treatment. The pr...
A Review Study on Various Anti-Microbial Susceptibility Patterns of Staphylococcus aureus
Abstract: Staphylococcus aureus stays a standout amongst the most much of the time segregated pathogens in both group and hospital practices. The organism form has been observed to be the most widely recognized bacterial...