Henoch Schönlein Purpura in children: Clinical features and risk factors for renal involvement
Journal Title: Medical Science and Discovery - Year 2018, Vol 5, Issue 7
Abstract
Objective: This study aimed to evaluate the clinical and laboratory features of children diagnosed with Henoch Schönlein purpura (HSP), risk factors of renal involvement and their effect on prognosis. Methods: A total of 80 pediatric HSP patients (44 males and 36 females) between ages 2 to 13 (average age 7.68±3.09) admitted to the Pediatrics Clinic and follow-up cases from the Pediatric Rheumatology and Nephrology Clinic of the Istanbul Medeniyet University, Göztepe Training and Research Hospital, between April 1998 and June 2003 were enrolled for the study. In order to precisely evaluate glomerular and tubular function, urinary β 2 microglobulin, microalbumin and tubular reabsorption of phosphorus (TRP) were determined. Results: A retrospective evaluation of the HSP patients showed that 26 (32.5%) had symptoms of renal impairment. In terms of renal function, 20 (25%) out of the 54 asymptomatic children initially subjected to routine renal tests had renal involvement. In terms of age, there was a significant difference (p < 0.016) in developing renal involvement between patients above 5 years old and those younger than 5 years. Conclusion: It was therefore suggested that long-term follow-ups in addition to examinations such as routine kidney function tests, tubular reabsorption of phosphate (TRP) and microalbumin levels should be conducted in order to detect the early phase of renal damage.
Authors and Affiliations
Atiye Fedakar
Keywords
Related Articles
- EP ID EP520683
- DOI 10.17546/msd.432588
- Views 45
- Downloads 0
Neuroprotective Effects of Boric Acid against Fluoride Toxicity on Rat Synaptosomes
Objective: Fluoride toxicity primarily contributes to the production of reactive oxygen and nitrogen derivatives, trigger the cell death pathways by causing lipid peroxidation and DNA damage. Boric acid (BA) contribute...
Acute myeloid leukemia under lenalidomide therapy in a patient with multiple myeloma
A 53-year-old patient who had a 7 year history of multiple myeloma was diagnosed with high risk myelodysplastic syndrome while on lenalidomide treatment. Progression to acute myeloid leukemia has occurred during the foll...
Educational needs of patients undergoing coronary artery bypass graft
Introduction: Cardiac surgery associates with potential physiological, mental, emotional , growth and spiritual consequences due to the existence of many stressful factors. Training and learning patients can minimize ris...
Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery
One year old patient followed with tetralogy of fallot (TOF) was admitted to our service for surgical repair. Ventricular septal defect (VSD) was repaired with a Dacron patch. The infundibular muscle was resected to all...
The State and Importance Of Motorcycle Injuries In Progression With Trauma Etiologies
Objective: Motorcycle injuries have shown a progression in last years in trauma patients admitted to our clinic. The aim of this study is to evaluate statistically whether the motorcycle accidents’ incidence is really ha...