Henoch-Schonleinpurpura with Sickle Cell Disease- A Rare Presentation
Journal Title: IJAR-Indian Journal of Applied Research - Year 2015, Vol 5, Issue 10
Abstract
Henoch-Schonlein purpura (HSP) also known as Anaphylactoidpurpura or purpura rheumatic,is a disease of skin and other organs. Disease presents with palpable purpura with Joint, Kidney and abdomin- al in volvement. HSP is a type of systemic vasculitis that means inflammation of blood vessels caused by deposition of immune- com plexes containing the IgA antibody, the exact cause is not known. It is self limiting disease, usually resolves within- sev eral weeks without treatment. Systemic steroid are recommended for moderate to severe HSP. Steroid therapies lead to complete resolution of the symptoms. Sickle cell disease is hereditary blood disorder associated with abnormality in the oxygen carrying hemoglobi-n mol ecule in red blood cells. This lead to abnormal shape of red blood cell that is rigid, sickle like shape associated with haemolysis, severe infection, pain (sickle cell crisis) and stroke. Sickle cell disease is common in tribal people of central India. The prevalence has ranged from 9.4 to 22.2% in endemic areas of Madhya Pradesh, Rajasthan and Chhattisgarh.
Authors and Affiliations
Dr. Jaswant Mahawer, Dr. Varun Singh Paliwal, Dr. Rohit Bhardwaj, Dr. Ambrish Gupta, Dr. Dulari J. Gandhi, Dr. Kushagra Gupta
Keywords
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