Hepatic adenomatosis: A clinically challenging rare liver disease
Journal Title: Annals of Clinical Gastroenterology and Hepatology - Year 2018, Vol 2, Issue 1
Abstract
43-year-old lady presented with incidentally discovered liver lesions while she was being managed for her complaints of menorrhagia. CT and MRI showed hepatomegaly with multiple lesions in both lobes of the liver with vascular element in the background of diffuse fatty infiltration. Patient underwent laparoscopic core biopsy. Histopathology showed extensive steatosis, intracytoplasmic giant mitochondria and absence of portal tracts, features highly suggestive of hepatic adenomatosis. IHC staining showed membranous and cytoplasmic positivity in hepatocytes for B-catenin consistent with multiple hepatic adenomatosis. Hepatic adenomatosis is a new clinical entity in the hepatological practice characterized by the presence of 10 or more nodules in the liver known for its major complication of bleeding. Hepatic adenomatosis is managed by regular imaging and resection of large (> 5cm) superficial and painful adenomas along with liver function tests and tumor markers to rule out malignant transformation. However, the potential cure being the liver transplantation.
Authors and Affiliations
Sunitha Ramachandra, Lakshmi Rao, Masoud Al Kindi
Keywords
Related Articles
- EP ID EP558216
- DOI 10.29328/journal.acgh.1001006
- Views 37
- Downloads 0
Analysis of Pyogenic Liver Abscesses
Background: Pyogenic liver abscesses (PLA) are frequent in immunosuppressed patients. We review the characteristics of patients with PLA at a tertiary academic Spanish hospital in Asturias. Methods: A retrospective obse...
Anemia due to a rare anomaly - Case Report
Anemia due to gastrointestinal blood loss can occur due to many conditions and rarely to bowel structural anomalies. We report a 12 years old girl with anemia due to small bowel duplication cyst, posing diagnostic challe...
A rare cause of obstructive jaundice - case report
Obstructive jaundice in children is not uncommon and has diverse etiologies. We report a rare cause of obstructive jaundice, cholangitis and pancreatic mass in a young boy due to eosinophilic cholangiopathy who responded...
The influence of Infliximab on the development of Experimental Pancreatitis
Aim: To identify the possibility of correction of motor function of the gastro-intestinal tract in experimental pancreatitis with the administration of infliximab.
Role of Accessory Right Inferior Hepatic Veins in evaluation of Liver Transplantation
Purpose: The purpose of the study is to access the prevalence of accessory right inferior hepatic veins and their relevant significance in liver transplantation. Materials and Methods: A retrospective study was done in...